Literature DB >> 18680710

Can exercise mimetics substitute for exercise?

Erik A Richter1, Bente Kiens, Jørgen F P Wojtaszewski.   

Abstract

Exercise leads to changes in muscle phenotype with important implications for exercise performance and health. A recent paper in Cell by Narkar et al. (2008) shows that many of the adaptations in muscle phenotype elicited by exercise can be mimicked by genetic manipulation and drug treatment in mice.

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Year:  2008        PMID: 18680710     DOI: 10.1016/j.cmet.2008.07.004

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  14 in total

1.  Should Willy Wonka have been a sports nutritionist?

Authors:  Andrew Philp
Journal:  J Physiol       Date:  2011-10-01       Impact factor: 5.182

Review 2.  Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.

Authors:  Christian K Roberts; Andrea L Hevener; R James Barnard
Journal:  Compr Physiol       Date:  2013-01       Impact factor: 9.090

Review 3.  Novel pharmacological approaches to combat obesity and insulin resistance: targeting skeletal muscle with 'exercise mimetics'.

Authors:  A L Carey; B A Kingwell
Journal:  Diabetologia       Date:  2009-06-23       Impact factor: 10.122

Review 4.  Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery.

Authors:  F W Booth; M J Laye
Journal:  J Physiol       Date:  2009-09-01       Impact factor: 5.182

5.  MicroRNA as Novel Exercise Mimetic for Muscle Wasting in CKD.

Authors:  Robert H Mak; Wai W Cheung
Journal:  J Am Soc Nephrol       Date:  2017-07-18       Impact factor: 10.121

Review 6.  From gene engineering to gene modulation and manipulation: can we prevent or detect gene doping in sports?

Authors:  Giuseppe Fischetto; Stéphane Bermon
Journal:  Sports Med       Date:  2013-10       Impact factor: 11.136

7.  Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling.

Authors:  Chunying Li; Michaella M Reif; Siobhan M Craige; Shashi Kant; John F Keaney
Journal:  Nitric Oxide       Date:  2016-03-14       Impact factor: 4.427

8.  Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy.

Authors:  Jeffrey J Brault; Jakob G Jespersen; Alfred L Goldberg
Journal:  J Biol Chem       Date:  2010-04-19       Impact factor: 5.157

9.  Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise.

Authors:  Steve R Roof; Lifei Tang; Joseph E Ostler; Muthu Periasamy; Sandor Györke; George E Billman; Mark T Ziolo
Journal:  Basic Res Cardiol       Date:  2013-02-04       Impact factor: 17.165

Review 10.  PPARs and the cardiovascular system.

Authors:  Milton Hamblin; Lin Chang; Yanbo Fan; Jifeng Zhang; Y Eugene Chen
Journal:  Antioxid Redox Signal       Date:  2009-06       Impact factor: 8.401

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