| Literature DB >> 18680381 |
Christian B Rauhut1, Laurin Melzig, Paul Knochel.
Abstract
The aryl sulfoxide moiety (ArSO) allows an expedient two-step meta-, para-difunctionalization of readily available diaryl sulfoxides. In the first step, the sulfoxide plays the role of a directing metalation group. In the second step, triggered by i-PrMgCl x LiCl, it becomes a leaving group and undergoes a regioselective sulfoxide-magnesium exchange.Entities:
Year: 2008 PMID： 18680381 DOI： 10.1021/ol801431z
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005