Yun-hong Wang1, Hong-fang Yin. 1. Department of Pathology, Peking University First Hospital, Beijing, China. gnikchina@yahoo.com.cn
Abstract
OBJECTIVE: Reporting a rare case with Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE), who also has nephrotic syndrome resulting from minimal change glomerulopathy. METHODS: Histological manifestations, immunohistochemical staining, immunofluorescence staining, and electron microscope were performed. RESULTS: One 37-year-old male patient with recurrent erythra, cutaneous node, painless cervical lymph node enlargement and nephrotic syndrome in 5 years. It's confirmed through biopsies that the subcutaneous node is ALHE, the cervical lymph node is kimura disease, and renal lesion is minimal change glomerulopathy. CONCLUSION: Kimura disease and ALHE may be different features of the same disease, and may complicate glomerulopathy.
OBJECTIVE: Reporting a rare case with Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE), who also has nephrotic syndrome resulting from minimal change glomerulopathy. METHODS: Histological manifestations, immunohistochemical staining, immunofluorescence staining, and electron microscope were performed. RESULTS: One 37-year-old male patient with recurrent erythra, cutaneous node, painless cervical lymph node enlargement and nephrotic syndrome in 5 years. It's confirmed through biopsies that the subcutaneous node is ALHE, the cervical lymph node is kimura disease, and renal lesion is minimal change glomerulopathy. CONCLUSION:Kimura disease and ALHE may be different features of the same disease, and may complicate glomerulopathy.