Literature DB >> 18675590

Will new antischistosomal drugs finally emerge?

Donato Cioli1, Cristiana Valle, Francesco Angelucci, Adriana E Miele.   

Abstract

It has been often observed that the chemotherapeutic armamentarium against an important disease such as schistosomiasis consists of just one drug, praziquantel. Thus, development of drug resistance is an impending danger, with serious implications for the health protection of many millions of people. This rational and legitimate concern might now begin to be relieved by the recent proposal of a new class of compounds that could represent a novel source of drugs against schistosomiasis.

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Year:  2008        PMID: 18675590     DOI: 10.1016/j.pt.2008.05.006

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  31 in total

1.  Evaluation of an IgY-based immunomagnetic enzyme-linked immunosorbent assay system for detection of circulating Schistosoma japonicum antigen in serum samples from patients in China.

Authors:  Jia-hui Lei; Bing-tao Su; Hong Xu; Ji-long Shen; Xiao-hong Guan; Zhen-qing Feng; Yong-long Li; Ming-xing Xu; Wen-qi Liu
Journal:  Am J Trop Med Hyg       Date:  2011-12       Impact factor: 2.345

2.  Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice.

Authors:  Hong-jun Li; Wei Wang; Guo-li Qu; You-zi Li; Yong-hui Tao; Yun-tian Xing; Xiao-ting Wang; Yang Dai; Jian-ying Wei; Jian-rong Dai; Gerald C Coles; You-sheng Liang
Journal:  Parasitol Res       Date:  2011-10-18       Impact factor: 2.289

3.  In vitro and in vivo activities of arachidonic acid against Schistosoma mansoni and Schistosoma haematobium.

Authors:  Rashika El Ridi; Marwa Aboueldahab; Hatem Tallima; Mohamed Salah; Noha Mahana; Samia Fawzi; Shadia H Mohamed; Omar M Fahmy
Journal:  Antimicrob Agents Chemother       Date:  2010-05-17       Impact factor: 5.191

4.  Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.

Authors:  Hong-Jun Li; Wei Wang; You-Zi Li; Guo-Li Qu; Yun-Tian Xing; Yong-Hui Tao; Jian-Ying Wei; Jian-Rong Dai; You-Sheng Liang
Journal:  Parasitol Res       Date:  2011-05-28       Impact factor: 2.289

5.  Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography.

Authors:  Francesco Angelucci; Daniela Dimastrogiovanni; Giovanna Boumis; Maurizio Brunori; Adriana E Miele; Fulvio Saccoccia; Andrea Bellelli
Journal:  J Biol Chem       Date:  2010-07-21       Impact factor: 5.157

6.  Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.

Authors:  Tolulope T Oke; Jackob Moskovitz; David L Williams
Journal:  J Parasitol       Date:  2009-12       Impact factor: 1.276

Review 7.  Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites.

Authors:  David L Williams; Mariana Bonilla; Vadim N Gladyshev; Gustavo Salinas
Journal:  Antioxid Redox Signal       Date:  2012-10-03       Impact factor: 8.401

8.  Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths.

Authors:  Lucía Otero; Mariana Bonilla; Anna V Protasio; Cecilia Fernández; Vadim N Gladyshev; Gustavo Salinas
Journal:  BMC Genomics       Date:  2010-04-13       Impact factor: 3.969

9.  Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.

Authors:  Francesco Angelucci; Ahmed A Sayed; David L Williams; Giovanna Boumis; Maurizio Brunori; Daniela Dimastrogiovanni; Adriana E Miele; Frida Pauly; Andrea Bellelli
Journal:  J Biol Chem       Date:  2009-08-26       Impact factor: 5.157

10.  Histopathological changes in adult Schistosoma japonicum harbored in mice treated with a single dose of mefloquine.

Authors:  Chao-Wei Zhang; Shu-Hua Xiao; Jürg Utzinger; Jacques Chollet; Jennifer Keiser; Marcel Tanner
Journal:  Parasitol Res       Date:  2009-02-17       Impact factor: 2.289

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