Literature DB >> 18672934

Studies directed toward the development of amide-linked RNA mimics: synthesis of the monomeric building blocks.

Tushar Kanti Chakraborty1, Praveen Kumar Gajula, Dipankar Koley.   

Abstract

A general approach toward the synthesis of all four monomeric building blocks of the ribonucleoside amino acids 3'-amino-5'-carboxymethyl-3',5'-dideoxy nucleosides in their protected forms is described that will facilitate the development of amide-linked RNA mimics.

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Year:  2008        PMID: 18672934     DOI: 10.1021/jo801156a

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  A convergent synthesis of carbocyclic sinefungin and its C5 epimer.

Authors:  Arun K Ghosh; Kai Lv
Journal:  European J Org Chem       Date:  2014-10-01

2.  Synthesis and gene silencing properties of siRNAs containing terminal amide linkages.

Authors:  Maria Gaglione; M Emilia Mercurio; Nicoletta Potenza; Nicola Mosca; Aniello Russo; Ettore Novellino; Sandro Cosconati; Anna Messere
Journal:  Biomed Res Int       Date:  2014-03-26       Impact factor: 3.411

  2 in total

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