Literature DB >> 18672878

Four-component benzyne coupling reactions: a concise total synthesis of dehydroaltenuene B.

Darunee Soorukram1, Tao Qu, Anthony G M Barrett.   

Abstract

A four-component coupling reaction of 3,5-dimethoxybenzyne with 2-methyl-2-cyclohexenylmagnesium chloride, carbon dioxide, and iodine was utilized as a key step in the first total synthesis of dehydroaltenuene B.

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Year:  2008        PMID： 18672878     DOI： 10.1021/ol8015435

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthesis of 2H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes.

Authors:  Yuesi Fang; Chunrui Wu; Richard C Larock; Feng Shi
Journal:  J Org Chem       Date:  2011-10-12       Impact factor: 4.354

2.  Synthesis of dihydrobenzisoxazoles by the [3 + 2] cycloaddition of arynes and oxaziridines.

Authors:  Arif Kivrak; Richard C Larock
Journal:  J Org Chem       Date:  2010-11-05       Impact factor: 4.354

3.  Asymmetric synthesis of quaternary aryl amino acid derivatives via a three-component aryne coupling reaction.

Authors:  Elizabeth P Jones; Peter Jones; Andrew J P White; Anthony G M Barrett
Journal:  Beilstein J Org Chem       Date:  2011-11-25       Impact factor: 2.883

4.  Concise enantiospecific total synthesis of tubingensin A.

Authors:  Adam E Goetz; Amanda L Silberstein; Michael A Corsello; Neil K Garg
Journal:  J Am Chem Soc       Date:  2014-02-18       Impact factor: 15.419
  4 in total

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