PURPOSE: To evaluate the interexaminer and intraexaminer reliability of macular microperimetry using the microperimeter MP-1. METHODS PARTICIPANTS: Fifteen healthy volunteers younger than 40 years of age (Group 1), 15 healthy subjects over 60 years (Group 2), and five patients with age-related macular degeneration (Group 3). OBSERVATION PROCEDURE: Two examiners (E1 and E2) measured, in random order, interexaminer (E2-E1a) reliability. Another examination was undergone by one of the examiners a week later to evaluate the intraexaminer (E1b-E1a) reliability. MAIN OUTCOME MEASURES: Macular sensitivity (mean threshold (decibel)) and stability of fixation were determined using MP1 microperimetry. Agreement was analysed by means of Bland-Altman plots and by the determination of the intraclass correlation coefficient.ResultsThe interexaminer (E2-E1a) and the intraexaminer (E1b-E1a) differences in the mean threshold values were not statistically significant (P=0.850, 95% confidence Interval (CI)=-0.265 to 0.319; P=0.246, 95% CI=-0.099 to 0.375, respectively). Limits of agreement and intraclass correlation coefficients also showed good agreement in each group. CONCLUSIONS: A good reliability was found for the mean threshold values in all the three groups, indicating examiner-independent measurements.
PURPOSE: To evaluate the interexaminer and intraexaminer reliability of macular microperimetry using the microperimeter MP-1. METHODS PARTICIPANTS: Fifteen healthy volunteers younger than 40 years of age (Group 1), 15 healthy subjects over 60 years (Group 2), and five patients with age-related macular degeneration (Group 3). OBSERVATION PROCEDURE: Two examiners (E1 and E2) measured, in random order, interexaminer (E2-E1a) reliability. Another examination was undergone by one of the examiners a week later to evaluate the intraexaminer (E1b-E1a) reliability. MAIN OUTCOME MEASURES: Macular sensitivity (mean threshold (decibel)) and stability of fixation were determined using MP1 microperimetry. Agreement was analysed by means of Bland-Altman plots and by the determination of the intraclass correlation coefficient.ResultsThe interexaminer (E2-E1a) and the intraexaminer (E1b-E1a) differences in the mean threshold values were not statistically significant (P=0.850, 95% confidence Interval (CI)=-0.265 to 0.319; P=0.246, 95% CI=-0.099 to 0.375, respectively). Limits of agreement and intraclass correlation coefficients also showed good agreement in each group. CONCLUSIONS: A good reliability was found for the mean threshold values in all the three groups, indicating examiner-independent measurements.
Authors: Arthika Chandramohan; Sandra S Stinnett; John T Petrowski; Stefanie G Schuman; Cynthia A Toth; Scott W Cousins; Eleonora M Lad Journal: Retina Date: 2016-05 Impact factor: 4.256