Literature DB >> 18670406

Do inflammatory cytokine genes confer susceptibility to diabetic nephropathy?

Shiro Maeda1.   

Abstract

Microinflammation has been recognized as an important process for the progression of diabetic nephropathy. Inflammatory cytokines, such as interleukin-6 produced by infiltrating cells or renal cells, play important roles in the pathogenesis of diabetic nephropathy. Although the mechanisms underlying the regulation of these cytokines in the kidneys of patients with diabetes mellitus remain unclear, genetic variations in the genes encoding the inflammatory cytokines might confer susceptibility to the disease by altering their functions or expressions.

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Year:  2008        PMID： 18670406     DOI： 10.1038/ki.2008.291

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  7 in total

1.  Fenofibrate attenuates tubulointerstitial fibrosis and inflammation through suppression of nuclear factor-κB and transforming growth factor-β1/Smad3 in diabetic nephropathy.

Authors:  Lingyun Li; Nerimiah Emmett; David Mann; Xueying Zhao
Journal:  Exp Biol Med (Maywood)       Date:  2010-03

2.  Overexpression of acetyl-coenzyme A carboxylase beta increases proinflammatory cytokines in cultured human renal proximal tubular epithelial cells.

Authors:  Masa-aki Kobayashi; Hirotaka Watada; Ryuzo Kawamori; Shiro Maeda
Journal:  Clin Exp Nephrol       Date:  2010-06-01       Impact factor: 2.801

3.  Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model.

Authors:  Hanna Shevalye; Roman Stavniichuk; Weizheng Xu; Jie Zhang; Sergey Lupachyk; Yury Maksimchyk; Viktor R Drel; Elizabeth Z Floyd; Barbara Slusher; Irina G Obrosova
Journal:  Biochem Pharmacol       Date:  2009-11-27       Impact factor: 5.858

4.  Combined acute hyperglycemic and hyperinsulinemic clamp induced profibrotic and proinflammatory responses in the kidney.

Authors:  Meenalakshmi M Mariappan; Kristin DeSilva; Gian Pio Sorice; Giovanna Muscogiuri; Fabio Jimenez; Seema Ahuja; Jefferey L Barnes; Goutam Ghosh Choudhury; Nicolas Musi; Ralph DeFronzo; Balakuntalam S Kasinath
Journal:  Am J Physiol Cell Physiol       Date:  2013-10-09       Impact factor: 4.249

5.  MiRNA-29c regulates the expression of inflammatory cytokines in diabetic nephropathy by targeting tristetraprolin.

Authors:  Jia Guo; Jing Li; Jing Zhao; Shuguang Yang; Luyao Wang; Genyang Cheng; Dong Liu; Jing Xiao; Zhangsuo Liu; Zhanzheng Zhao
Journal:  Sci Rep       Date:  2017-05-24       Impact factor: 4.379

6.  Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.

Authors:  Tarunveer Singh Ahluwalia; Madhu Khullar; Monica Ahuja; Harbir Singh Kohli; Anil Bhansali; Viswanathan Mohan; Radha Venkatesan; Taranjit Singh Rai; Kamal Sud; Pawan K Singal
Journal:  PLoS One       Date:  2009-04-09       Impact factor: 3.240

7.  High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells.

Authors:  Hong Feng; Junling Gu; Fang Gou; Wei Huang; Chenlin Gao; Guo Chen; Yang Long; Xueqin Zhou; Maojun Yang; Shuang Liu; Shishi Lü; Qiaoyan Luo; Yong Xu
Journal:  J Diabetes Res       Date:  2016-01-05       Impact factor: 4.011
  7 in total

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