PURPOSE OF REVIEW: Bladder cancer is the most expensive tumor with regard to both costs per patient per year and lifetime costs per patient. Nonmuscle invasive tumors account for the highest share of the overall costs for bladder cancer. Costs for follow-up (excluding costs for reinterventions) compared with transurethral resection and cystectomy account for a considerably lower portion of the overall costs. RECENT FINDINGS: From an economic standpoint, the biggest potential for savings could, therefore, be in the treatment and re-treatment of nonmuscle invasive tumors. Cost reductions have already been demonstrated with a reduction of hospital admission for such treatments, use of photodynamic diagnosis supported transurethral resection to avoid residual tumors, and adjuvant chemoinstillation and immunoinstillation to prolong or prevent tumor recurrences. SUMMARY: Further cost reductions can be achieved with a centralization of patients undergoing cystectomy by shifting these patients to high-volume surgeons in high-volume hospitals, thereby reducing complications and length of hospital stay. In advanced stages predictive markers may identify suitable subgroups for molecular therapies and, therefore, avoid costs of inappropriate treatments.
PURPOSE OF REVIEW: Bladder cancer is the most expensive tumor with regard to both costs per patient per year and lifetime costs per patient. Nonmuscle invasive tumors account for the highest share of the overall costs for bladder cancer. Costs for follow-up (excluding costs for reinterventions) compared with transurethral resection and cystectomy account for a considerably lower portion of the overall costs. RECENT FINDINGS: From an economic standpoint, the biggest potential for savings could, therefore, be in the treatment and re-treatment of nonmuscle invasive tumors. Cost reductions have already been demonstrated with a reduction of hospital admission for such treatments, use of photodynamic diagnosis supported transurethral resection to avoid residual tumors, and adjuvant chemoinstillation and immunoinstillation to prolong or prevent tumor recurrences. SUMMARY: Further cost reductions can be achieved with a centralization of patients undergoing cystectomy by shifting these patients to high-volume surgeons in high-volume hospitals, thereby reducing complications and length of hospital stay. In advanced stages predictive markers may identify suitable subgroups for molecular therapies and, therefore, avoid costs of inappropriate treatments.
Authors: Peter J Bostrom; Paul J Toren; Hao Xi; Raymond Chow; Tran Truong; Justin Liu; Kelly Lane; Laura Legere; Anjum Chagpar; Alexandre R Zlotta; Antonio Finelli; Neil E Fleshner; Ethan D Grober; Michael A S Jewett Journal: J Am Med Inform Assoc Date: 2011-08-04 Impact factor: 4.497
Authors: Johannes Mischinger; Lutz Philipp Guttenberg; Jörg Hennenlotter; Georgios Gakis; Stefan Aufderklamm; Steffen Rausch; Eva Neumann; Jens Bedke; Stefan Kruck; Christian Schwentner; Arnulf Stenzl; Tilman Todenhöfer Journal: J Cancer Res Clin Oncol Date: 2016-12-02 Impact factor: 4.553
Authors: Marcus Horstmann; Heike Bontrup; Jörg Hennenlotter; Dirk Taeger; Anne Weber; Beate Pesch; Gerhard Feil; Oliver Patschan; Georg Johnen; Arnulf Stenzl; Thomas Brüning Journal: World J Urol Date: 2010-03-23 Impact factor: 4.226
Authors: Michael Rink; Helena Furberg; Emily C Zabor; Evanguelos Xylinas; Marko Babjuk; Armin Pycha; Yair Lotan; Pierre I Karakiewicz; Giacomo Novara; Brian D Robinson; Francesco Montorsi; Felix K Chun; Douglas S Scherr; Shahrokh F Shariat Journal: Eur Urol Date: 2012-08-21 Impact factor: 20.096
Authors: Jessica De Long; Travis B Sullivan; John Humphrey; Tanya Logvinenko; Kelly A Summerhayes; Spencer Kozinn; Niall Harty; Ian C Summerhayes; John A Libertino; Antonia H Holway; Kimberly M Rieger-Christ Journal: Am J Transl Res Date: 2015-11-15 Impact factor: 4.060
Authors: Tanzeela Khalid; Paul White; Ben De Lacy Costello; Raj Persad; Richard Ewen; Emmanuel Johnson; Chris S Probert; Norman Ratcliffe Journal: PLoS One Date: 2013-07-08 Impact factor: 3.240
Authors: E Xylinas; M Kent; L Kluth; A Pycha; E Comploj; R S Svatek; Y Lotan; Q-D Trinh; P I Karakiewicz; S Holmang; D S Scherr; M Zerbib; A J Vickers; S F Shariat Journal: Br J Cancer Date: 2013-08-27 Impact factor: 7.640