Literature DB >> 18670272

Can we still afford bladder cancer?

Arnulf Stenzl1, Joerg Hennenlotter, David Schilling.   

Abstract

PURPOSE OF REVIEW: Bladder cancer is the most expensive tumor with regard to both costs per patient per year and lifetime costs per patient. Nonmuscle invasive tumors account for the highest share of the overall costs for bladder cancer. Costs for follow-up (excluding costs for reinterventions) compared with transurethral resection and cystectomy account for a considerably lower portion of the overall costs. RECENT
FINDINGS: From an economic standpoint, the biggest potential for savings could, therefore, be in the treatment and re-treatment of nonmuscle invasive tumors. Cost reductions have already been demonstrated with a reduction of hospital admission for such treatments, use of photodynamic diagnosis supported transurethral resection to avoid residual tumors, and adjuvant chemoinstillation and immunoinstillation to prolong or prevent tumor recurrences.
SUMMARY: Further cost reductions can be achieved with a centralization of patients undergoing cystectomy by shifting these patients to high-volume surgeons in high-volume hospitals, thereby reducing complications and length of hospital stay. In advanced stages predictive markers may identify suitable subgroups for molecular therapies and, therefore, avoid costs of inappropriate treatments.

Entities:  

Mesh:

Year:  2008        PMID: 18670272     DOI: 10.1097/MOU.0b013e32830b8925

Source DB:  PubMed          Journal:  Curr Opin Urol        ISSN: 0963-0643            Impact factor:   2.309


  12 in total

1.  Point-of-care clinical documentation: assessment of a bladder cancer informatics tool (eCancerCareBladder): a randomized controlled study of efficacy, efficiency and user friendliness compared with standard electronic medical records.

Authors:  Peter J Bostrom; Paul J Toren; Hao Xi; Raymond Chow; Tran Truong; Justin Liu; Kelly Lane; Laura Legere; Anjum Chagpar; Alexandre R Zlotta; Antonio Finelli; Neil E Fleshner; Ethan D Grober; Michael A S Jewett
Journal:  J Am Med Inform Assoc       Date:  2011-08-04       Impact factor: 4.497

2.  Comparison of different concepts for interpretation of chromosomal aberrations in urothelial cells detected by fluorescence in situ hybridization.

Authors:  Johannes Mischinger; Lutz Philipp Guttenberg; Jörg Hennenlotter; Georgios Gakis; Stefan Aufderklamm; Steffen Rausch; Eva Neumann; Jens Bedke; Stefan Kruck; Christian Schwentner; Arnulf Stenzl; Tilman Todenhöfer
Journal:  J Cancer Res Clin Oncol       Date:  2016-12-02       Impact factor: 4.553

Review 3.  Inflammation and Cancer: What Can We Therapeutically Expect from Checkpoint Inhibitors?

Authors:  Johannes Mischinger; Eva Comperat; Christian Schwentner; Arnulf Stenzl; Georgios Gakis
Journal:  Curr Urol Rep       Date:  2015-09       Impact factor: 3.092

4.  Clinical experience with survivin as a biomarker for urothelial bladder cancer.

Authors:  Marcus Horstmann; Heike Bontrup; Jörg Hennenlotter; Dirk Taeger; Anne Weber; Beate Pesch; Gerhard Feil; Oliver Patschan; Georg Johnen; Arnulf Stenzl; Thomas Brüning
Journal:  World J Urol       Date:  2010-03-23       Impact factor: 4.226

5.  [Quality of care in patients with newly diagnosed bladder cancer: a prospective assessment in northern Germany].

Authors:  C Reek; M Rink; M Bloch; J Hansen; F K Chun; A Schneider; J Busche; M Fisch
Journal:  Urologe A       Date:  2013-07       Impact factor: 0.639

6.  Polymer-enhanced adenoviral transduction of CAR-negative bladder cancer cells.

Authors:  Laura M Kasman; Sutapa Barua; Ping Lu; Kaushal Rege; Christina Voelkel-Johnson
Journal:  Mol Pharm       Date:  2009 Sep-Oct       Impact factor: 4.939

7.  Impact of smoking and smoking cessation on oncologic outcomes in primary non-muscle-invasive bladder cancer.

Authors:  Michael Rink; Helena Furberg; Emily C Zabor; Evanguelos Xylinas; Marko Babjuk; Armin Pycha; Yair Lotan; Pierre I Karakiewicz; Giacomo Novara; Brian D Robinson; Francesco Montorsi; Felix K Chun; Douglas S Scherr; Shahrokh F Shariat
Journal:  Eur Urol       Date:  2012-08-21       Impact factor: 20.096

8.  A non-invasive miRNA based assay to detect bladder cancer in cell-free urine.

Authors:  Jessica De Long; Travis B Sullivan; John Humphrey; Tanya Logvinenko; Kelly A Summerhayes; Spencer Kozinn; Niall Harty; Ian C Summerhayes; John A Libertino; Antonia H Holway; Kimberly M Rieger-Christ
Journal:  Am J Transl Res       Date:  2015-11-15       Impact factor: 4.060

9.  A pilot study combining a GC-sensor device with a statistical model for the identification of bladder cancer from urine headspace.

Authors:  Tanzeela Khalid; Paul White; Ben De Lacy Costello; Raj Persad; Richard Ewen; Emmanuel Johnson; Chris S Probert; Norman Ratcliffe
Journal:  PLoS One       Date:  2013-07-08       Impact factor: 3.240

10.  Accuracy of the EORTC risk tables and of the CUETO scoring model to predict outcomes in non-muscle-invasive urothelial carcinoma of the bladder.

Authors:  E Xylinas; M Kent; L Kluth; A Pycha; E Comploj; R S Svatek; Y Lotan; Q-D Trinh; P I Karakiewicz; S Holmang; D S Scherr; M Zerbib; A J Vickers; S F Shariat
Journal:  Br J Cancer       Date:  2013-08-27       Impact factor: 7.640

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