Literature DB >> 18670126

Cyanopeptoline CB071: a cyclic depsipeptide isolated from the freshwater cyanobacterium Aphanocapsa sp.

Hyukjae Choi1, Sun Kwan Oh, Wonho Yih, Jungwook Chin, Heonjoong Kang, Jung-Rae Rho.   

Abstract

Cyanopeptolin CB071 (1), a trypsin inhibitor, was isolated from the freshwater cyanobacterium Aphanocapsa sp. Its complete structure was determined by detailed NMR spectroscopy and MS analyses, along with chemical reactions. The compound showed inhibition of trypsin at a concentration of IC50=2.5 microM.

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Year:  2008        PMID: 18670126     DOI: 10.1248/cpb.56.1191

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

Review 1.  Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.

Authors:  George E Chlipala; Shunyan Mo; Jimmy Orjala
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Draft Genome Sequence of Exopolysaccharide-Producing Cyanobacterium Aphanocapsa montana BDHKU 210001.

Authors:  Sourav Bhattacharyya; Mathu Malar Chandrababunaidu; Deeya Sen; Arijit Panda; Arpita Ghorai; Sushma Bhan; Neha Sanghi; Sucheta Tripathy
Journal:  Genome Announc       Date:  2015-03-05

3.  Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411.

Authors:  Hanna Mazur-Marzec; Anna Fidor; Marta Cegłowska; Ewa Wieczerzak; Magdalena Kropidłowska; Marie Goua; Jenny Macaskill; Christine Edwards
Journal:  Mar Drugs       Date:  2018-06-26       Impact factor: 5.118

  3 in total

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