Literature DB >> 18669998

Predicting suicide attempts in young adults with histories of childhood abuse.

Jelena Brezo1, Joel Paris, Frank Vitaro, Martine Hébert, Richard E Tremblay, Gustavo Turecki.   

Abstract

BACKGROUND: Although childhood abuse is an important correlate of suicidality, not all individuals who were abused as children attempt suicide. AIMS: To identify correlates and moderators of suicide attempts in adults reporting childhood physical abuse, contact sexual abuse, or both.
METHOD: A French-Canadian, school-based cohort (n=1684) was prospectively followed.
RESULTS: The identity of the abuser moderated the relationship of abuse frequency and suicide attempts, with individuals abused by their immediate family being at highest risk. Although paternal education exhibited negative associations (OR=0.71, 95% CI 0.58-0.88), several externalising phenotypes had positive associations with suicide attempts: disruptive disorders (OR=3.10, 95% CI 1.05-9.15), conduct problems (OR=1.09, 95% CI 1.01-1.19) and childhood aggression (OR=1.41, 95% CI 1.08-1.83).
CONCLUSIONS: Characteristics of the abuser and abusive acts may be important additional indicators of risk for suicide attempts. Future research needs to employ developmental approaches to examine the extent and mechanisms by which childhood abuse contributes to the shared variance of suicidality, maladaptive traits and psychopathology.

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Year:  2008        PMID: 18669998     DOI: 10.1192/bjp.bp.107.037994

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  49 in total

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Authors:  Laura P Chen; M Hassan Murad; Molly L Paras; Kristina M Colbenson; Amelia L Sattler; Erin N Goranson; Mohamed B Elamin; Richard J Seime; Gen Shinozaki; Larry J Prokop; Ali Zirakzadeh
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Review 2.  Life adversities and suicidal behavior in young individuals: a systematic review.

Authors:  Gianluca Serafini; Caterina Muzio; Giulia Piccinini; Eirini Flouri; Gabriella Ferrigno; Maurizio Pompili; Paolo Girardi; Mario Amore
Journal:  Eur Child Adolesc Psychiatry       Date:  2015-08-25       Impact factor: 4.785

3.  Suicidality in the prospective Zurich study: prevalence, risk factors and gender.

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Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2014-03-30       Impact factor: 5.270

4.  Effect of childhood general traumas on suicide attempt depends on TPH2 and ADARB1 variants in psychiatric patients.

Authors:  Jelena Karanović; Maja Ivković; Vladimir M Jovanović; Saša Šviković; Maja Pantović-Stefanović; Miloš Brkušanin; Aleksandar Damjanović; Goran Brajušković; Dušanka Savić-Pavićević
Journal:  J Neural Transm (Vienna)       Date:  2017-01-13       Impact factor: 3.575

Review 5.  DNA methylation and childhood maltreatment: from animal models to human studies.

Authors:  P-E Lutz; G Turecki
Journal:  Neuroscience       Date:  2013-08-08       Impact factor: 3.590

Review 6.  Suicide and suicidal behaviour.

Authors:  Gustavo Turecki; David A Brent
Journal:  Lancet       Date:  2015-09-15       Impact factor: 79.321

7.  Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.

Authors:  Patrick O McGowan; Aya Sasaki; Ana C D'Alessio; Sergiy Dymov; Benoit Labonté; Moshe Szyf; Gustavo Turecki; Michael J Meaney
Journal:  Nat Neurosci       Date:  2009-03       Impact factor: 24.884

8.  Sex, Gender, and Suicidal Behavior.

Authors:  Maria Luisa Barrigon; Fanny Cegla-Schvartzman
Journal:  Curr Top Behav Neurosci       Date:  2020

9.  Childhood determinants of adult psychiatric disorder.

Authors:  Tom Fryers; Traolach Brugha
Journal:  Clin Pract Epidemiol Ment Health       Date:  2013-02-22

10.  Association of polyaminergic loci with anxiety, mood disorders, and attempted suicide.

Authors:  Laura M Fiori; Brigitte Wanner; Valérie Jomphe; Jordie Croteau; Frank Vitaro; Richard E Tremblay; Alexandre Bureau; Gustavo Turecki
Journal:  PLoS One       Date:  2010-11-30       Impact factor: 3.240

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