Literature DB >> 18668827

The effect of diazepam on human gastric secretion.

D Birnbaum, F Karmeli, M Tefera.   

Abstract

Human basal gastric secretion is markedly reduced after oral administration of 10 mg diazepam. This effect lasts for five hours.Gastric nocturnal secretion, collected five hours after the last meal, reveals a decline towards the morning hours with an average of 25% in placebo-treated patients. A comparison between placebo and diazepam reveals a significantly greater decrease of 47% in volume after giving parenterally 10 mg diazepam without noticeable side effects.

Entities:  

Year:  1971        PMID: 18668827      PMCID: PMC1411758          DOI: 10.1136/gut.12.8.616

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  4 in total

1.  GASTRIC RESPONSE TO FOODS.

Authors:  R J Miller; O Bergeim; P B Hawk
Journal:  Science       Date:  1920-09-10       Impact factor: 47.728

2.  The influence of oral diazepam on gastrointestinal motility. A preliminary report.

Authors:  D Birnbaum; J Ben-Menachem; A Schwartz
Journal:  Am J Proctol       Date:  1970-08

3.  Effect of diazepam on human salivary secretion.

Authors:  J E Steiner; D Birnbaum; F Karmeli; S Cohen
Journal:  Digestion       Date:  1970       Impact factor: 3.216

4.  Effects of psychotropic drugs on pressor responses to central and peripheral stimulation in cat.

Authors:  W Schallek; F Zabransky
Journal:  Arch Int Pharmacodyn Ther       Date:  1966-05
  4 in total
  5 in total

1.  Inhibitory effect of bromazepam on basal and betazole-stimulated gastric acid secretion in man.

Authors:  G Stacher; D Stärker
Journal:  Gut       Date:  1974-02       Impact factor: 23.059

2.  Effect of intravenous diazepam on human lower oesophageal sphincter pressure under controlled double blind crossover conditions.

Authors:  T R Weihrauch; C F Förster; H Köhler; K Ewe; J Krieglstein
Journal:  Gut       Date:  1979-01       Impact factor: 23.059

3.  Benzodiazepines reduce gastric ulcers induced in rats by stress.

Authors:  S E File; J B Pearce
Journal:  Br J Pharmacol       Date:  1981-11       Impact factor: 8.739

4.  Ranitidine versus ranitidine and prazepam in the short-term treatment of duodenal ulcer--a double-blind controlled trial.

Authors:  C Hüscher; G Magni; A Salmi; S Bossini; C Felini; F Besozzi; D de Leo
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

5.  [Comparative study on the effect of anticholinergic substances on basic gastric secretion as well as on gastric secretion stimulated by pentagastrin or hypoglycemia (author's transl)].

Authors:  K Kutz; G Schuler; U Brenner; S E Miederer
Journal:  Klin Wochenschr       Date:  1976-05-15
  5 in total

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