Literature DB >> 18668500

Enantioselective nucleophilic catalysis: the synthesis of aza-beta-lactams through [2+2] cycloadditions of ketenes with azo compounds.

Jacob M Berlin1, Gregory C Fu.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18668500      PMCID： PMC2790040          DOI： 10.1002/anie.200802439

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  10 in total

1.  Nucleophilic chiral amines as catalysts in asymmetric synthesis.

Authors:  Stefan France; David J Guerin; Scott J Miller; Thomas Lectka
Journal:  Chem Rev       Date:  2003-08       Impact factor: 60.622

2.  Catalytic asymmetric synthesis of piperidine derivatives through the [4 + 2] annulation of imines with allenes.

Authors:  Ryan P Wurz; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2005-09-07       Impact factor: 15.419

3.  Synthesis of functionalized cyclopentenes through catalytic asymmetric [3+2] cycloadditions of allenes with enones.

Authors:  Jonathan E Wilson; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2006-02-20       Impact factor: 15.336

4.  Catalytic asymmetric synthesis of tertiary alkyl chlorides.

Authors:  Elaine C Lee; Kevin M McCauley; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

Review 5.  Recent approaches towards the asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids.

Authors:  Henning Vogt; Stefan Bräse
Journal:  Org Biomol Chem       Date:  2006-11-30       Impact factor: 3.876

6.  Enantioselective synthesis of protected amines by the catalytic asymmetric addition of hydrazoic acid to ketenes.

Authors:  Xing Dai; Takashi Nakai; Jan A C Romero; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

7.  Enantioselective Staudinger synthesis of beta-lactams catalyzed by a planar-chiral nucleophile.

Authors:  Brian L Hodous; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2002-02-27       Impact factor: 15.419

8.  Asymmetric synthesis of highly substituted beta-lactones by nucleophile-catalyzed [2+2] cycloadditions of disubstituted ketenes with aldehydes.

Authors:  Jonathan E Wilson; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2004-11-26       Impact factor: 15.336

9.  Catalytic asymmetric Staudinger reactions to form beta-lactams: an unanticipated dependence of diastereoselectivity on the choice of the nitrogen substituent.

Authors:  Elaine C Lee; Brian L Hodous; Enda Bergin; Crystal Shih; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2005-08-24       Impact factor: 15.419

10.  Asymmetric catalysis with "planar-chiral" derivatives of 4-(dimethylamino)pyridine.

Authors:  Gregory C Fu
Journal:  Acc Chem Res       Date:  2004-08       Impact factor: 22.384
  10 in total
  8 in total

1.  Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1.

Authors:  Daniel A Bachovchin; Andrea M Zuhl; Anna E Speers; Monique R Wolfe; Eranthie Weerapana; Steven J Brown; Hugh Rosen; Benjamin F Cravatt
Journal:  J Med Chem       Date:  2011-06-30       Impact factor: 7.446

2.  Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.

Authors:  Andrea M Zuhl; Justin T Mohr; Daniel A Bachovchin; Sherry Niessen; Ku-Lung Hsu; Jacob M Berlin; Maximilian Dochnahl; María P López-Alberca; Gregory C Fu; Benjamin F Cravatt
Journal:  J Am Chem Soc       Date:  2012-03-08       Impact factor: 15.419

Review 3.  The pharmacological landscape and therapeutic potential of serine hydrolases.

Authors:  Daniel A Bachovchin; Benjamin F Cravatt
Journal:  Nat Rev Drug Discov       Date:  2012-01-03       Impact factor: 84.694

4.  Catalytic, asymmetric reactions of ketenes and ketene enolates.

Authors:  Daniel H Paull; Anthony Weatherwax; Thomas Lectka
Journal:  Tetrahedron       Date:  2009-08-22       Impact factor: 2.457

Review 5.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

6.  Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors.

Authors:  Daniel A Bachovchin; Justin T Mohr; Anna E Speers; Chu Wang; Jacob M Berlin; Timothy P Spicer; Virneliz Fernandez-Vega; Peter Chase; Peter S Hodder; Stephan C Schürer; Daniel K Nomura; Hugh Rosen; Gregory C Fu; Benjamin F Cravatt
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-11       Impact factor: 11.205

7.  Catalytic asymmetric cycloaddition of ketenes and nitroso compounds: enantioselective synthesis of alpha-hydroxycarboxylic acid derivatives.

Authors:  Maximilian Dochnahl; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

8.  Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived β-lactone.

Authors:  Neil J Lajkiewicz; Armand B Cognetta; Micah J Niphakis; Benjamin F Cravatt; John A Porco
Journal:  J Am Chem Soc       Date:  2014-02-04       Impact factor: 15.419
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.