| Literature DB >> 18666797 |
Mercedes Amat1, Maria Pérez, Annamaria T Minaglia, Joan Bosch.
Abstract
A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.Entities:
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Year: 2008 PMID： 18666797 DOI： 10.1021/jo801172b
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354