PURPOSE: To examine the ability of TrueFISP imaging for evaluating tumor size in mouse brain at high field. MATERIALS AND METHODS: Brains of healthy and glioma-implanted nude mice were imaged at 4.7T and 9.4T. 3D imaging was performed with TrueFISP and T2w-RARE. Radiofrequency pulses with alternating phase and the sum-of-squares reconstruction method were used in TrueFISP imaging. The contrast-to-noise ratio (CNR) was evaluated in healthy and in tumoral brain regions. RESULTS: Banding artifact was correctly suppressed in TrueFISP images thanks to the method used. The signal-to-noise ratio (SNR) and CNR were comparable in TrueFISP and T2w-RARE images at 4.7T, but acquisition was around 4 times shorter with TrueFISP. Tumor was well detected at 4.7T with TrueFISP, but CNR between tumor and healthy tissue was low at 9.4T. CONCLUSION: TrueFISP is efficient and fast to perform brain imaging at 4.7T. Multiple TrueFISP acquisitions with phase-cycled radiofrequency (RF) pulses and sum-of-squares reconstruction allow suppression of banding artifact. Tumoral regions were well detected and the method allows longitudinal studies of tumor growth. (c) 2008 Wiley-Liss, Inc.
PURPOSE: To examine the ability of TrueFISP imaging for evaluating tumor size in mouse brain at high field. MATERIALS AND METHODS: Brains of healthy and glioma-implantednude mice were imaged at 4.7T and 9.4T. 3D imaging was performed with TrueFISP and T2w-RARE. Radiofrequency pulses with alternating phase and the sum-of-squares reconstruction method were used in TrueFISP imaging. The contrast-to-noise ratio (CNR) was evaluated in healthy and in tumoral brain regions. RESULTS: Banding artifact was correctly suppressed in TrueFISP images thanks to the method used. The signal-to-noise ratio (SNR) and CNR were comparable in TrueFISP and T2w-RARE images at 4.7T, but acquisition was around 4 times shorter with TrueFISP. Tumor was well detected at 4.7T with TrueFISP, but CNR between tumor and healthy tissue was low at 9.4T. CONCLUSION: TrueFISP is efficient and fast to perform brain imaging at 4.7T. Multiple TrueFISP acquisitions with phase-cycled radiofrequency (RF) pulses and sum-of-squares reconstruction allow suppression of banding artifact. Tumoral regions were well detected and the method allows longitudinal studies of tumor growth. (c) 2008 Wiley-Liss, Inc.
Authors: Ying Gao; Yong Chen; Dan Ma; Yun Jiang; Kelsey A Herrmann; Jason A Vincent; Katherine M Dell; Mitchell L Drumm; Susann M Brady-Kalnay; Mark A Griswold; Chris A Flask; Lan Lu Journal: NMR Biomed Date: 2015-02-02 Impact factor: 4.044
Authors: Emeline J Ribot; Francisco M Martinez-Santiesteban; Carmen Simedrea; Patricia S Steeg; Ann F Chambers; Brian K Rutt; Paula J Foster Journal: J Magn Reson Imaging Date: 2011-07 Impact factor: 4.813
Authors: Dean B Percy; Emeline J Ribot; Yuhua Chen; Catherine McFadden; Carmen Simedrea; Patricia S Steeg; Ann F Chambers; Paula J Foster Journal: Invest Radiol Date: 2011-11 Impact factor: 6.016