Literature DB >> 18665610

Miniaturized low-cost ion mobility spectrometer for fast detection of chemical warfare agents.

Stefan Zimmermann1, Sebastian Barth, Wolfgang K M Baether, Joachim Ringer.   

Abstract

Ion mobility spectrometry (IMS) is a well-known method for detecting hazardous compounds in air. Typical applications are the detection of chemical warfare agents, highly toxic industrial compounds, explosives, and drugs of abuse. Detection limits in the low part per billion range, fast response times, and simple instrumentation make this technique more and more popular. In particular, there is an increasing demand for miniaturized low-cost IMS for hand-held devices and air monitoring of public areas by sensor networks. In this paper, we present a miniaturized aspiration condenser type ion mobility spectrometer for fast detection of chemical warfare agents. The device is easy to manufacture and allows single substance identification down to low part per billion-level concentrations within seconds. The improved separation power results from ion focusing by means of geometric constraints and fluid dynamics. A simple pattern recognition algorithm is used for the identification of trained substances in air. The device was tested at the German Armed Forces Scientific Institute for Protection Technologies-NBC-Protection. Different chemical warfare agents, such as sarin, tabun, soman, US-VX, sulfur mustard, nitrogen mustard, and lewisite were tested. The results are presented here.

Entities:  

Year:  2008        PMID: 18665610     DOI: 10.1021/ac800559h

Source DB:  PubMed          Journal:  Anal Chem        ISSN: 0003-2700            Impact factor:   6.986


  6 in total

Review 1.  Materials and transducers toward selective wireless gas sensing.

Authors:  Radislav A Potyrailo; Cheryl Surman; Nandini Nagraj; Andrew Burns
Journal:  Chem Rev       Date:  2011-09-07       Impact factor: 60.622

2.  Discriminative potential of ion mobility spectrometry for the detection of fentanyl and fentanyl analogues relative to confounding environmental interferents.

Authors:  Thomas P Forbes; Jeffrey Lawrence; Jennifer R Verkouteren; R Michael Verkouteren
Journal:  Analyst       Date:  2019-10-03       Impact factor: 4.616

Review 3.  Review on ion mobility spectrometry. Part 2: hyphenated methods and effects of experimental parameters.

Authors:  R Cumeras; E Figueras; C E Davis; J I Baumbach; I Gràcia
Journal:  Analyst       Date:  2015-03-07       Impact factor: 4.616

4.  Ion mobility spectrometry nuisance alarm threshold analysis for illicit narcotics based on environmental background and a ROC-curve approach.

Authors:  Thomas P Forbes; Marcela Najarro
Journal:  Analyst       Date:  2016-05-20       Impact factor: 4.616

5.  Portable FAIMS: Applications and Future Perspectives.

Authors:  Michael T Costanzo; Jared J Boock; Robin H J Kemperman; Michael S Wei; Christopher R Beekman; Richard A Yost
Journal:  Int J Mass Spectrom       Date:  2016-12-08       Impact factor: 1.986

6.  A Novel Microwave-Induced Plasma Ionization Source for Ion Mobility Spectrometry.

Authors:  Jianxiong Dai; Zhongjun Zhao; Gaoling Liang; Yixiang Duan
Journal:  Sci Rep       Date:  2017-03-13       Impact factor: 4.379

  6 in total

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