Literature DB >> 18665593

An expedient asymmetric synthesis of platencin.

K C Nicolaou1, Qiao-Yan Toh, David Y-K Chen.   

Abstract

A short and efficient synthesis of enone 3, a key intermediate in the total synthesis of platencin (2), based on an intramolecular Diels-Alder reaction is described.

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Year:  2008        PMID: 18665593     DOI: 10.1021/ja804588r

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  15 in total

1.  Studies toward the synthesis of maoecrystal V.

Authors:  Zhenhua Gu; Armen Zakarian
Journal:  Org Lett       Date:  2011-01-27       Impact factor: 6.005

Review 2.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

3.  Controlling the facial selectivity of asymmetric [4+2] cyclo-additions: a concise synthesis of the cis-decalin core structure of superstolides A and B.

Authors:  Lei Chen; Zhengmao Hua; Gangqin Li; Zhendong Jin
Journal:  Org Lett       Date:  2011-06-14       Impact factor: 6.005

Review 4.  A brief history of antibiotics and select advances in their synthesis.

Authors:  Kyriacos C Nicolaou; Stephan Rigol
Journal:  J Antibiot (Tokyo)       Date:  2017-07-05       Impact factor: 2.649

5.  Total synthesis of maoecrystal V: early-stage C-H functionalization and lactone assembly by radical cyclization.

Authors:  Ping Lu; Zhenhua Gu; Armen Zakarian
Journal:  J Am Chem Soc       Date:  2013-09-23       Impact factor: 15.419

6.  A symmetry-based concise formal synthesis of platencin, a novel lead against "superbugs".

Authors:  Arun K Ghosh; Kai Xi
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

7.  Synthesis and antibacterial properties of (-)-nor-platencin.

Authors:  Olga V Barykina; Kerri L Rossi; Michael J Rybak; Barry B Snider
Journal:  Org Lett       Date:  2009-11-19       Impact factor: 6.005

8.  Total syntheses of (+/-)-platencin and (-)-platencin.

Authors:  K C Nicolaou; G Scott Tria; David J Edmonds; Moumita Kar
Journal:  J Am Chem Soc       Date:  2009-11-04       Impact factor: 15.419

9.  The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis.

Authors:  Allen Y Hong; Brian M Stoltz
Journal:  European J Org Chem       Date:  2013-05-01

10.  A synthesis of the carbon skeleton of maoecrystal V.

Authors:  Paul J Krawczuk; Niklas Schöne; Phil S Baran
Journal:  Org Lett       Date:  2009-11-05       Impact factor: 6.005

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