Literature DB >> 18665329

A cross-sectional study of the Anticoagulation Clinic in RIPAS Hospital, Brunei.

Linda Y Y Lim1, Vui Heng Chong, Nallathamby Rajendran, Wai See Wong.   

Abstract

BACKGROUND: The number of patients seen at the RIPAS Hospital Anticoagulation Clinic (ACC) has increased cumulatively over the years. With patient numbers increasing dramatically, a study of the anticoagulant service has become necessary to determine the clinic's performance.
OBJECTIVES: The aim of this study was to gather descriptive data on the ACC and to determine the percentage of patients' international normalised ratio (INR) results within target, below target and above target at the ACC.
METHODS: A cross-sectional study was conducted for all patients attending the ACC in 2005 and 2006. Patient data were collected from their warfarin chart. The results were compared between the 2 years.
RESULTS: The numbers of patients were 364 and 390 in 2005 and 2006, respectively. The male-to-female ratio was 0.95 in 2005 and 1.14 in 2006. There was no significant change in ethnic distribution between the 2 years. Most of the patients seen at the ACC were Malays, followed by Chinese and other ethnicities consisting of Caucasian, Burmese, Bisaya, Gurkha, Iban and Filipino. There was a shift in the age of population in 2006 (mean = 60.2 +/- 14.0) compared to 2005 (mean = 58.1 +/- 14.1). Of the patients, 34.6% had multiple indications requiring anticoagulation in 2005 and 29.5% in 2006. The most common indications for patients were atrial fibrillation (63% in 2005 and 61% in 2006), prosthetic valve replacement (22% in 2005 and 18% in 2006) and thrombosis (4% in 2005 and 2006). These three indications accounted for 90% of patients seen. In 2005, 33.4% of INR were below target, 49.3% within target and 17.3% above target. In 2006, 36% were below target, 51.1% were within target and 12.9% were above target.
CONCLUSION: This was the first time such a study was conducted for the ACC. It helped us gauge our current performance, understand our practice and enable us to implement any necessary changes to improve the clinic.

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Year:  2008        PMID: 18665329     DOI: 10.1007/s11239-008-0257-3

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  12 in total

Review 1.  Interaction of warfarin with drugs, natural substances, and foods.

Authors:  David J Greenblatt; Lisa L von Moltke
Journal:  J Clin Pharmacol       Date:  2005-02       Impact factor: 3.126

2.  Guidelines on oral anticoagulation (warfarin): third edition--2005 update.

Authors:  T P Baglin; D M Keeling; H G Watson
Journal:  Br J Haematol       Date:  2006-02       Impact factor: 6.998

3.  Impact of adherence, knowledge, and quality of life on anticoagulation control.

Authors:  Nichola J Davis; Henny H Billett; Hillel W Cohen; Julia H Arnsten
Journal:  Ann Pharmacother       Date:  2005-02-15       Impact factor: 3.154

4.  Audit of anticoagulant therapy.

Authors:  P E Rose
Journal:  J Clin Pathol       Date:  1996-01       Impact factor: 3.411

Review 5.  Effect of study setting on anticoagulation control: a systematic review and metaregression.

Authors:  Carl van Walraven; Alison Jennings; Natalie Oake; Dean Fergusson; Alan J Forster
Journal:  Chest       Date:  2006-05       Impact factor: 9.410

6.  Outpatient oral anticoagulant management--an audit of 82 patients.

Authors:  N Kakkar; R Kaur; Mary John
Journal:  J Assoc Physicians India       Date:  2005-10

Review 7.  Systematic overview of warfarin and its drug and food interactions.

Authors:  Anne M Holbrook; Jennifer A Pereira; Renee Labiris; Heather McDonald; James D Douketis; Mark Crowther; Philip S Wells
Journal:  Arch Intern Med       Date:  2005-05-23

Review 8.  Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Authors:  Daniel E Singer; Gregory W Albers; James E Dalen; Alan S Go; Jonathan L Halperin; Warren J Manning
Journal:  Chest       Date:  2004-09       Impact factor: 9.410

Review 9.  Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Authors:  Harry R Büller; Giancarlo Agnelli; Russel D Hull; Thomas M Hyers; Martin H Prins; Gary E Raskob
Journal:  Chest       Date:  2004-09       Impact factor: 9.410

10.  Relationship between patients' warfarin knowledge and anticoagulation control.

Authors:  Elaine Othilia Y L Tang; Cemen S M Lai; Kenneth K C Lee; Raymond S M Wong; Gregory Cheng; Thomas Y K Chan
Journal:  Ann Pharmacother       Date:  2003-01       Impact factor: 3.154

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