Literature DB >> 18664840

Computed tomographic distinction of perirenal liposarcoma from exophytic angiomyolipoma: a feature analysis study.

James J Ellingson1, Fergus V Coakley, Bonnie N Joe, Aliya Qayyum, Antonio C Westphalen, Benjamin M Yeh.   

Abstract

PURPOSE: To identify computed tomographic (CT) findings that distinguish perirenal liposarcomas from exophytic angiomyolipomas.
MATERIALS AND METHODS: We identified CT scans of 20 patients (13 women and 7 men; mean age, 63 years) with either perirenal liposarcoma (n = 11) proven at histopathology or large exophytic angiomyolipomas (n = 9) determined by 2-year stability (n = 6) or histopathology (n = 3). Two independent readers unaware of the final diagnoses recorded the presence of the following CT findings: (1) tumoral vessel extending into the renal cortex, (2) tumoral vessel extending into the renal hilum, (3) renal parenchymal defect at the site of tumor contact, (4) intratumoral hemorrhage, (5) nonfat attenuating intratumoral nodules, and (6) calcification.
RESULTS: A tumoral vessel extending into the renal cortex was seen only in angiomyolipomas (7 and 6 of 9 patients versus 0 and 0 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.005 for both). A parenchymal defect was more commonly seen in angiomyolipomas (7 and 6 of 9 angiomyolipomas versus 1 and 1 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.05 for both). Calcifications were seen by both readers in 6 of 11 liposarcomas but not in any angiomyolipomas (P < 0.05). The other recorded findings were not useful in distinguishing CT features (P > 0.1 for both readers).
CONCLUSIONS: In the evaluation of a fatty perinephric mass at CT, the presence of a tumoral vessel extending into the renal cortex or a renal parenchymal defect at the site of tumor contact strongly favors the diagnosis of exophytic angiomyolipoma, whereas calcifications suggest liposarcoma.

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Year:  2008        PMID: 18664840      PMCID: PMC2748260          DOI: 10.1097/RCT.0b013e3181507534

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  8 in total

1.  Computerized tomography characteristics that differentiate angiomyolipomas from liposarcomas in the perinephric space.

Authors:  Li-Jen Wang; Yon-Cheong Wong; Chi-Jen Chen; Lai-Chu See
Journal:  J Urol       Date:  2002-02       Impact factor: 7.450

2.  Renal angiomyolipomas and HMB-45 reactivity.

Authors:  R Ashfaq; A G Weinberg; J Albores-Saavedra
Journal:  Cancer       Date:  1993-05-15       Impact factor: 6.860

Review 3.  Surgical management of primary retroperitoneal liposarcomas.

Authors:  I Karanikas; T Liakakos; S Koundourakis; A Papadopoulos; M Garsallah; S Dendrinos
Journal:  Acta Chir Belg       Date:  1993 Jul-Aug       Impact factor: 1.090

4.  The natural history of renal angiomyolipoma.

Authors:  M S Steiner; S M Goldman; E K Fishman; F F Marshall
Journal:  J Urol       Date:  1993-12       Impact factor: 7.450

5.  Primary dedifferentiated liposarcoma of the retroperitoneum. Prognostic significance of computed tomography and magnetic resonance imaging features.

Authors:  Ukihide Tateishi; Tadashi Hasegawa; Yasuo Beppu; Mitsuo Satake; Noriyuki Moriyama
Journal:  J Comput Assist Tomogr       Date:  2003 Sep-Oct       Impact factor: 1.826

6.  Appearance and distinguishing features of retroperitoneal calcifications at computed tomography.

Authors:  Patric Kroepil; Fergus V Coakley; Anno Graser; Richard S Breiman; Aliya Qayyum; Benjamin M Yeh
Journal:  J Comput Assist Tomogr       Date:  2003 Nov-Dec       Impact factor: 1.826

7.  CT differentiation of large exophytic renal angiomyolipomas and perirenal liposarcomas.

Authors:  Gary M Israel; Morton A Bosniak; Chrystia M Slywotzky; Robert J Rosen
Journal:  AJR Am J Roentgenol       Date:  2002-09       Impact factor: 3.959

8.  Renal angiomyolipoma: growth followed up with CT and/or US.

Authors:  L Lemaitre; Y Robert; F Dubrulle; M Claudon; A Duhamel; P Danjou; E Mazeman
Journal:  Radiology       Date:  1995-12       Impact factor: 11.105

  8 in total
  11 in total

Review 1.  Spermatic cord myxoid liposarcoma presenting as an incarcerated inguinal hernia: report of a case and review of literatures.

Authors:  Y-F Hsu; Y-Y Chou; Y H Cheng
Journal:  Hernia       Date:  2011-03-09       Impact factor: 4.739

2.  A case of pararenal angiomyolipoma arising from an existing exophytic angiomyolipoma.

Authors:  Michael Lipsky; Ingride Richardson; Bassir Tareen
Journal:  Can Urol Assoc J       Date:  2010-06       Impact factor: 1.862

3.  Cross-sectional Imaging Features of Primary Retroperitoneal Tumors and Their Subsequent Treatment.

Authors:  Turker Acar; Mustafa Harman; Serkan Guneyli; Kazim Gemici; Duran Efe; Ibrahim Guler; Melda Yildiz
Journal:  J Clin Imaging Sci       Date:  2015-04-30

Review 4.  Renal angiomyolipoma: a radiological classification and update on recent developments in diagnosis and management.

Authors:  Masahiro Jinzaki; Stuart G Silverman; Hirotaka Akita; Yoji Nagashima; Shuji Mikami; Mototsugu Oya
Journal:  Abdom Imaging       Date:  2014-06

Review 5.  Radiological diagnosis of perinephric pathology: pictorial essay 2015.

Authors:  Goran Mitreski; Tom Sutherland
Journal:  Insights Imaging       Date:  2017-01-03

6.  Solid renal masses in adults.

Authors:  Mahesh Kumar Mittal; Binit Sureka
Journal:  Indian J Radiol Imaging       Date:  2016 Oct-Dec

Review 7.  Recommendations for imaging-based diagnosis and management of renal angiomyolipoma associated with tuberous sclerosis complex.

Authors:  María José Buj Pradilla; Teresa Martí Ballesté; Roser Torra; Felipe Villacampa Aubá
Journal:  Clin Kidney J       Date:  2017-09-11

8.  Multidetector Computed Tomography Features in Differentiating Exophytic Renal Angiomyolipoma from Retroperitoneal Liposarcoma: A Strobe-Compliant Observational Study.

Authors:  Qiushi Wang; Yu-Hsiang Juan; Yong Li; Jia-Jun Xie; Hui Liu; Hongfei Huang; Zaiyi Liu; Junhui Zheng; Ujwala S Saboo; Sachin S Saboo; Changhong Liang
Journal:  Medicine (Baltimore)       Date:  2015-09       Impact factor: 1.817

9.  Giant bilateral angiomyolipomas with spontaneous hemorrhage and inferior vena cava thrombosis in a patient with tuberous sclerosis.

Authors:  Meriem Menany; Safae Khnaba; Bouchaib Radouane; Mohamed Jidal; Touriya Amil; Rachida Saouab
Journal:  Pan Afr Med J       Date:  2017-07-25

10.  Renal angiomyolipoma with renal vein thrombosis: an incidental finding.

Authors:  Elisa Melo Abreu; Teresa Margarida Cunha
Journal:  BJR Case Rep       Date:  2016-02-19
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