Literature DB >> 18664377

Cytotoxic activity screening of some indigenous Thai plants.

P Prayong1, S Barusrux, N Weerapreeyakul.   

Abstract

The 50% ethanolic extracts from 14 plant species used in Thai traditional folklore were screened for cytotoxic activity against a malignant human hepatoma (HepG2) cell line and a normal African green monkey kidney (Vero) cell line. The extracts of Polyalthia evecta and Erythroxylum cuneatum showed potent anticancer activity in the HepG2 cell line with IC(50) of 70+/-3 microg/ml and 64+/-4 microg/ml, respectively. P. evecta demonstrated more selectivity to the HepG2 than the Vero cell (selectivity index>14.3) indicating its potential for biopharmaceutical use.

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Year:  2008        PMID： 18664377     DOI： 10.1016/j.fitote.2008.06.007

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  47 in total

1.  Synergistic anticancer effect of the extracts from Polyalthia evecta caused apoptosis in human hepatoma (HepG2) cells.

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Journal:  Asian Pac J Trop Biomed       Date:  2012-08

2.  Anticancer effect of the extracts from Polyalthia evecta against human hepatoma cell line (HepG2).

Authors:  Sasipawan Machana; Natthida Weerapreeyakul; Sahapat Barusrux
Journal:  Asian Pac J Trop Biomed       Date:  2012-05

3.  Combinational effects of hexane insoluble fraction of Ficus septica Burm. F. and doxorubicin chemotherapy on T47D breast cancer cells.

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4.  Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells.

Authors:  Yhiya M Amen; Qinchang Zhu; Hai-Bang Tran; Mohamed S Afifi; Ahmed F Halim; Ahmed Ashour; Amira Mira; Kuniyoshi Shimizu
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5.  In vitro cytotoxic screening of 31 crude extracts of Thai herbs on a chondrosarcoma cell line and primary chondrocytes and apoptotic effects of selected extracts.

Authors:  Napat Ruamrungsri; Puntita Siengdee; Korawan Sringarm; Siriwadee Chomdej; Siriwan Ongchai; Korakot Nganvongpanit
Journal:  In Vitro Cell Dev Biol Anim       Date:  2016-02-08       Impact factor: 2.416

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7.  The Evaluation of Cytotoxic Properties from CCB-2 Sugar Complexes Against TNBC and Non-TNBC Cells.

Authors:  Riris Istighfari Jenie; Rohmad Yudi Utomo; Ratna Asmah Susidarti; Dhania Novitasari; Mitsunori Kirihata; Edy Meiyanto
Journal:  Asian Pac J Cancer Prev       Date:  2021-01-01

8.  The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder.

Authors:  Chi-Chen Lu; Mei-Yi Lin; Syue-Yi Chen; Cheng-Huang Shen; Lih-Geeng Chen; Hsiao-Yen Hsieh; Michael W Y Chan; Cheng-Da Hsu
Journal:  BMC Complement Altern Med       Date:  2013-02-23       Impact factor: 3.659

9.  Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro.

Authors:  Wiratchanee Mahavorasirikul; Vithoon Viyanant; Wanna Chaijaroenkul; Arunporn Itharat; Kesara Na-Bangchang
Journal:  BMC Complement Altern Med       Date:  2010-09-28       Impact factor: 3.659

10.  Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line.

Authors:  Sasipawan Machana; Natthida Weerapreeyakul; Sahapat Barusrux; Apiyada Nonpunya; Bungorn Sripanidkulchai; Thaweesak Thitimetharoch
Journal:  Chin Med       Date:  2011-10-31       Impact factor: 5.455
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