Literature DB >> 18663656

Chick chorioallantoic membrane as an in situ biological membrane for pharmaceutical formulation development: a review.

Constance L L Saw1, Paul W S Heng, Celine V Liew.   

Abstract

The use of animals in research has always been a debatable issue. Over the past few decades, efforts have been made to reduce, replace, and refine experiments for ethical use of experimental animals. The use of chick chorioallantoic membrane (CAM) was one of the proposed alternatives to the Draize rabbit ocular irritation test with several advantages including simplicity, rapidity, sensitivity, ease of performance, and cost-effectiveness. The recent use of CAM in the development of pharmaceuticals and testing models to mimic human tissue, including drug transport across CAM, will be discussed in this review.

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Year:  2008        PMID： 18663656     DOI： 10.1080/03639040801974295

Source DB:  PubMed          Journal:  Drug Dev Ind Pharm        ISSN： 0363-9045            Impact factor:   3.225


  9 in total

1.  Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.

Authors:  Karin Jöhrer; Marlene Obkircher; Daniel Neureiter; Johanna Parteli; Claudia Zelle-Rieser; Eva Maizner; Johann Kern; Martin Hermann; Frank Hamacher; Olaf Merkel; Nathalie Wacht; Christian Zidorn; Marcel Scheideler; Richard Greil
Journal:  J Mol Med (Berl)       Date:  2011-12-29       Impact factor: 4.599

Review 2.  The chicken chorioallantoic membrane model in biology, medicine and bioengineering.

Authors:  Patrycja Nowak-Sliwinska; Tatiana Segura; M Luisa Iruela-Arispe
Journal:  Angiogenesis       Date:  2014-08-20       Impact factor: 9.596

Review 3.  The Chicken Embryo Chorioallantoic Membrane as an In Vivo Model for Photodynamic Therapy.

Authors:  Jaroslava Joniová; Georges Wagnières
Journal:  Methods Mol Biol       Date:  2022

4.  Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery.

Authors:  Rubén Varela-Fernández; Xurxo García-Otero; Victoria Díaz-Tomé; Uxía Regueiro; Maite López-López; Miguel González-Barcia; María Isabel Lema; Francisco Javier Otero-Espinar
Journal:  Pharmaceutics       Date:  2022-04-06       Impact factor: 6.525

Review 5.  The chick chorioallantoic membrane: a model of molecular, structural, and functional adaptation to transepithelial ion transport and barrier function during embryonic development.

Authors:  Maria Gabriella Gabrielli; Daniela Accili
Journal:  J Biomed Biotechnol       Date:  2010-03-21

6.  Real-time visualization and quantitation of vascular permeability in vivo: implications for drug delivery.

Authors:  Desmond B S Pink; Wendy Schulte; Missag H Parseghian; Andries Zijlstra; John D Lewis
Journal:  PLoS One       Date:  2012-03-29       Impact factor: 3.240

7.  Chick embryo chorioallantoic membrane (CAM): an alternative predictive model in acute toxicological studies for anti-cancer drugs.

Authors:  Chin Siang Kue; Kae Yi Tan; May Lynn Lam; Hong Boon Lee
Journal:  Exp Anim       Date:  2015-01-22

8.  Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins.

Authors:  Seah Ling Kuan; Stephan Fischer; Susanne Hafner; Tao Wang; Tatiana Syrovets; Weina Liu; Yu Tokura; David Yuen Wah Ng; Andreas Riegger; Christina Förtsch; Daniela Jäger; Thomas F E Barth; Thomas Simmet; Holger Barth; Tanja Weil
Journal:  Adv Sci (Weinh)       Date:  2018-06-14       Impact factor: 16.806

9.  SOCS2 correlates with malignancy and exerts growth-promoting effects in prostate cancer.

Authors:  Julia Hoefer; Johann Kern; Philipp Ofer; Iris E Eder; Georg Schäfer; Dimo Dietrich; Glen Kristiansen; Stephan Geley; Johannes Rainer; Eberhard Gunsilius; Helmut Klocker; Zoran Culig; Martin Puhr
Journal:  Endocr Relat Cancer       Date:  2014-01-30       Impact factor: 5.678
  9 in total

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