Literature DB >> 18663315

Characteristics of children with premature pubarche in the new york metropolitan area.

Alejandro Diaz1, Sonal Bhandari, Cristina Sison, Maria Vogiatzi.   

Abstract

BACKGROUND: Premature pubarche (PP) is defined as the appearance of pubic hair before 8 years in girls and 9 years in boys, without other signs of puberty. In the USA the prevalence of childhood overweight tripled between 1980 and 2000. An association between overweight and PP has been identified.
METHODS: We conducted a chart review to identify patients with the diagnosis of PP who were evaluated from July 2000 to October 2005. 38 patients, 29 females and 9 males, were studied. 16 were Caucasian, 11 African-American, 10 Hispanic, and 1 Arab. Age range was 4.3-9.8 years. Auxological features were analyzed.
RESULTS: Of the 38, 20 (52.6%) had a BMI >85th percentile. Increased weight was more common among females (62%) and Hispanics (80%). The study group was taller than expected Z = 1.11 +/- 0.95 (TH Z = 0.34 +/- 0.86). Among the 18 children who had bone age advancement >1.5 years, 10 (56%) had a predicted height <1 SD below the TH (p = 0.005).
CONCLUSIONS: In this study we confirmed the correlation between weight gain and PP. We also found that when the bone age was advanced >1.5 years, the predicted adult height was affected. Copyright 2008 S. Karger AG, Basel.

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Year:  2008        PMID: 18663315     DOI: 10.1159/000137661

Source DB:  PubMed          Journal:  Horm Res        ISSN: 0301-0163


  10 in total

1.  Retinol-binding protein 4 correlates with triglycerides but not insulin resistance in prepubertal children with and without premature adrenarche.

Authors:  Aviva B Sopher; Adrienne T Gerken; Eun-Ju Lee; William E Blaner; Stefanie Deeds; Dympna Gallagher; Dikoma C Shungu; Xiangling Mao; Abeer Hassoun; Donald J Mc Mahon; Sharon E Oberfield
Journal:  J Pediatr Endocrinol Metab       Date:  2011       Impact factor: 1.634

2.  Approach to the girl with early onset of pubic hair.

Authors:  Sharon E Oberfield; Aviva B Sopher; Adrienne T Gerken
Journal:  J Clin Endocrinol Metab       Date:  2011-06       Impact factor: 5.958

3.  Bone age advancement in prepubertal children with obesity and premature adrenarche: possible potentiating factors.

Authors:  Aviva B Sopher; Amy M Jean; Sarah K Zwany; Diana M Winston; Christy B Pomeranz; Jennifer J Bell; Donald J McMahon; Abeer Hassoun; Ilene Fennoy; Sharon E Oberfield
Journal:  Obesity (Silver Spring)       Date:  2011-02-10       Impact factor: 5.002

4.  Association between dehydroepiandrosterone sulphate levels at 7 years old and bone mineral density at 10 years old: a prospective cohort study.

Authors:  Rita Santos-Silva; Manuel Fontoura; Milton Severo; Raquel Lucas; Ana Cristina Santos
Journal:  Eur J Pediatr       Date:  2022-03-16       Impact factor: 3.183

5.  Association of dehydroepiandrosterone sulfate, birth size, adiposity and cardiometabolic risk factors in 7-year-old children.

Authors:  Rita Santos-Silva; Manuel Fontoura; João T Guimarães; Henrique Barros; Ana Cristina Santos
Journal:  Pediatr Res       Date:  2021-08-20       Impact factor: 3.953

Review 6.  Update on adrenarche.

Authors:  Selma Feldman Witchel; Bianca Pinto; Anne Claire Burghard; Sharon E Oberfield
Journal:  Curr Opin Pediatr       Date:  2020-08       Impact factor: 2.856

7.  Utility of early insulin response and proinsulin to assess insulin resistance.

Authors:  Amy M Jean; Abeer Hassoun; Jennifer Hughes; Christy Pomeranz; Ilene Fennoy; Donald J McMahon; Sharon E Oberfield
Journal:  J Pediatr       Date:  2009-07-29       Impact factor: 4.406

8.  Higher body fat and lower fat-free mass in girls with premature adrenarche.

Authors:  Ayşe Nurcan Cebeci; Ayşegül Taş
Journal:  J Clin Res Pediatr Endocrinol       Date:  2015-03

9.  Effects of Adrenal Androgen Levels on Bone Age Advancement in Prepubertal Children: Using the Ewha Birth and Growth Cohort Study.

Authors:  Jung Hyun Kwon; Hye Ah Lee; Young Ju Kim; Hwayoung Lee; Eun Ae Park; Su Jin Cho; Hye Sun Gwak; Eunhee Ha; Hyesook Park; Hae Soon Kim
Journal:  J Korean Med Sci       Date:  2017-06       Impact factor: 2.153

Review 10.  Adiposity Metabolic Consequences for Adolescent Bone Health.

Authors:  Kátia Gianlupi Lopes; Elisana Lima Rodrigues; Mariana Rodrigues da Silva Lopes; Valter Aragão do Nascimento; Arnildo Pott; Rita de Cássia Avellaneda Guimarães; Giovana Eliza Pegolo; Karine de Cássia Freitas
Journal:  Nutrients       Date:  2022-08-10       Impact factor: 6.706

  10 in total

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