Literature DB >> 18663021

Mutator genes giving rise to decreased antibiotic susceptibility in Pseudomonas aeruginosa.

Irith Wiegand1, Alexandra K Marr, Elena B M Breidenstein, Kristen N Schurek, Patrick Taylor, Robert E W Hancock.   

Abstract

Screening of the PA14 genomic transposon mutant library for resistance to ceftazidime, tobramycin, and ciprofloxacin led to the discovery of several mutants that appeared in more than one screen. Testing of the frequency of mutation to ciprofloxacin resistance revealed previously known mutator genes, including mutS and mutL, as well as mutators that have not yet been described for P. aeruginosa, including PA3958 and RadA (PA4609).

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18663021      PMCID： PMC2565895          DOI： 10.1128/AAC.00233-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Comprehensive transposon mutant library of Pseudomonas aeruginosa.

Authors:  Michael A Jacobs; Ashley Alwood; Iyarit Thaipisuttikul; David Spencer; Eric Haugen; Stephen Ernst; Oliver Will; Rajinder Kaul; Christopher Raymond; Ruth Levy; Liu Chun-Rong; Donald Guenthner; Donald Bovee; Maynard V Olson; Colin Manoil
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-14       Impact factor: 11.205

2.  Importance of uracil DNA glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich bacteria, in mutation prevention, tolerance to acidified nitrite, and endurance in mouse macrophages.

Authors:  Jeganathan Venkatesh; Pradeep Kumar; Pulukuri Sai Murali Krishna; Ramanathapuram Manjunath; Umesh Varshney
Journal:  J Biol Chem       Date:  2003-04-05       Impact factor: 5.157

3.  High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.

Authors:  A Oliver; R Cantón; P Campo; F Baquero; J Blázquez
Journal:  Science       Date:  2000-05-19       Impact factor: 47.728

4.  The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants.

Authors:  Antonio Oliver; Fernando Baquero; Jesús Blázquez
Journal:  Mol Microbiol       Date:  2002-03       Impact factor: 3.501

5.  Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathways.

Authors:  Robert G Fowler; Steven J White; Carol Koyama; Sean C Moore; Ronnie L Dunn; Roel M Schaaper
Journal:  DNA Repair (Amst)       Date:  2003-02-03

6.  Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions.

Authors:  Mark D Platt; Michael J Schurr; Karin Sauer; Gustavo Vazquez; Irena Kukavica-Ibrulj; Eric Potvin; Roger C Levesque; Amber Fedynak; Fiona S L Brinkman; Jill Schurr; Sung-Hei Hwang; Gee W Lau; Patrick A Limbach; John J Rowe; Michael A Lieberman; Nicolas Barraud; Jeremy Webb; Staffan Kjelleberg; Donald F Hunt; Daniel J Hassett
Journal:  J Bacteriol       Date:  2008-01-18       Impact factor: 3.490

7.  Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances.

Authors:  Irith Wiegand; Kai Hilpert; Robert E W Hancock
Journal:  Nat Protoc       Date:  2008       Impact factor: 13.491

8.  Characterization of the GO system of Pseudomonas aeruginosa.

Authors:  Antonio Oliver; Juan Manuel Sánchez; Jesús Blázquez
Journal:  FEMS Microbiol Lett       Date:  2002-11-19       Impact factor: 2.742

9.  Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis.

Authors:  Sara Montanari; Antonio Oliver; Paola Salerno; Ana Mena; Giovanni Bertoni; Burkhard Tümmler; Lisa Cariani; Massimo Conese; Gerd Döring; Alessandra Bragonzi
Journal:  Microbiology       Date:  2007-05       Impact factor: 2.777

10.  Hypermutability in environmental Pseudomonas aeruginosa and in populations causing pulmonary infection in individuals with cystic fibrosis.

Authors:  Dervla T Kenna; Catherine J Doherty; Juliet Foweraker; Lisa Macaskill; Victoria A Barcus; John R W Govan
Journal:  Microbiology (Reading)       Date:  2007-06       Impact factor: 2.777
View more
  16 in total

1.  Novel genetic determinants of low-level aminoglycoside resistance in Pseudomonas aeruginosa.

Authors:  Kristen N Schurek; Alexandra K Marr; Patrick K Taylor; Irith Wiegand; Lucie Semenec; Bhavjinder K Khaira; Robert E W Hancock
Journal:  Antimicrob Agents Chemother       Date:  2008-09-29       Impact factor: 5.191

Review 2.  Clinical significance of microbial infection and adaptation in cystic fibrosis.

Authors:  Alan R Hauser; Manu Jain; Maskit Bar-Meir; Susanna A McColley
Journal:  Clin Microbiol Rev       Date:  2011-01       Impact factor: 26.132

Review 3.  Hypermutation and stress adaptation in bacteria.

Authors:  R Jayaraman
Journal:  J Genet       Date:  2011-08       Impact factor: 1.166

4.  Genetic determinants involved in the susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.

Authors:  Carolina Alvarez-Ortega; Irith Wiegand; Jorge Olivares; Robert E W Hancock; José Luis Martínez
Journal:  Antimicrob Agents Chemother       Date:  2010-08-02       Impact factor: 5.191

Review 5.  Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms.

Authors:  Philip D Lister; Daniel J Wolter; Nancy D Hanson
Journal:  Clin Microbiol Rev       Date:  2009-10       Impact factor: 26.132

6.  Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa.

Authors:  Andreas Dötsch; Tanja Becker; Claudia Pommerenke; Zofia Magnowska; Lothar Jänsch; Susanne Häussler
Journal:  Antimicrob Agents Chemother       Date:  2009-03-30       Impact factor: 5.191

7.  Broad-Spectrum Adaptive Antibiotic Resistance Associated with Pseudomonas aeruginosa Mucin-Dependent Surfing Motility.

Authors:  Evelyn Sun; Erin E Gill; Reza Falsafi; Amy Yeung; Sijie Liu; Robert E W Hancock
Journal:  Antimicrob Agents Chemother       Date:  2018-08-27       Impact factor: 5.191

8.  On the molecular mechanism of GC content variation among eubacterial genomes.

Authors:  Hao Wu; Zhang Zhang; Songnian Hu; Jun Yu
Journal:  Biol Direct       Date:  2012-01-10       Impact factor: 4.540

9.  Genomewide screen for modulators of evolvability under toxic antibiotic exposure.

Authors:  Orsolya Méhi; Balázs Bogos; Bálint Csörgo; Csaba Pál
Journal:  Antimicrob Agents Chemother       Date:  2013-05-13       Impact factor: 5.191

10.  A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria.

Authors:  Clara Torres-Barceló; Gabriel Cabot; Antonio Oliver; Angus Buckling; R Craig Maclean
Journal:  Proc Biol Sci       Date:  2013-02-27       Impact factor: 5.349
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.