Literature DB >> 18663019

Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.

Véronique Dubois1, Laurent Poirel, François Demarthe, Corinne Arpin, Laure Coulange, Luciene A R Minarini, Marie-Christine Bezian, Patrice Nordmann, Claudine Quentin.   

Abstract

A clinical strain of Klebsiella pneumoniae was found to possess the chromosomal gene bla(SHV-56), encoding a new inhibitor-resistant beta-lactamase with a pI of 7.6. SHV-56 is derived from SHV-11 by the single substitution K234R. This mutation therefore evidences a new critical site for inhibitor resistance among SHV enzymes.

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Year:  2008        PMID: 18663019      PMCID: PMC2565901          DOI: 10.1128/AAC.00387-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  20 in total

1.  The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34.

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2.  Emergence in Klebsiella pneumoniae of a chromosome-encoded SHV beta-lactamase that compromises the efficacy of imipenem.

Authors:  Laurent Poirel; Claire Héritier; Isabelle Podglajen; Wladimir Sougakoff; Laurent Gutmann; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2003-02       Impact factor: 5.191

3.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

4.  High-level expression of chromosomally encoded SHV-1 beta-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae.

Authors:  L B Rice; L L Carias; A M Hujer; M Bonafede; R Hutton; C Hoyen; R A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

5.  SHV-49, a novel inhibitor-resistant beta-lactamase in a clinical isolate of Klebsiella pneumoniae.

Authors:  Véronique Dubois; Laurent Poirel; Corinne Arpin; Laure Coulange; Cécile Bebear; Patrice Nordmann; Claudine Quentin
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

Review 6.  Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe.

Authors:  R Cantón; A Novais; A Valverde; E Machado; L Peixe; F Baquero; T M Coque
Journal:  Clin Microbiol Infect       Date:  2008-01       Impact factor: 8.067

7.  Molecular epidemiology of an outbreak due to IRT-2 beta-lactamase-producing strains of Klebsiella pneumoniae in a geriatric department.

Authors:  D Girlich; A Karim; L Poirel; M H Cavin; C Verny; P Nordmann
Journal:  J Antimicrob Chemother       Date:  2000-04       Impact factor: 5.790

Review 8.  SHV-type beta-lactamases.

Authors:  L S Tzouvelekis; R A Bonomo
Journal:  Curr Pharm Des       Date:  1999-11       Impact factor: 3.116

9.  The use of analytical isoelectric focusing for detection and identification of beta-lactamases.

Authors:  A Mathew; A M Harris; M J Marshall; G W Ross
Journal:  J Gen Microbiol       Date:  1975-05

10.  Molecular characterization of a novel class 1 integron containing bla(GES-1) and a fused product of aac3-Ib/aac6'-Ib' gene cassettes in Pseudomonas aeruginosa.

Authors:  Véronique Dubois; Laurent Poirel; Caroline Marie; Corinne Arpin; Patrice Nordmann; Claudine Quentin
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

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  14 in total

1.  Variants of β-lactamase KPC-2 that are resistant to inhibition by avibactam.

Authors:  Krisztina M Papp-Wallace; Marisa L Winkler; Magdalena A Taracila; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2015-02-09       Impact factor: 5.191

2.  Biochemical study of a new inhibitor-resistant beta-lactamase, SHV-84, produced by a clinical Escherichia coli strain.

Authors:  Vera Manageiro; Eugénia Ferreira; Luís Albuquerque; Richard Bonnet; Manuela Caniça
Journal:  Antimicrob Agents Chemother       Date:  2010-03-08       Impact factor: 5.191

3.  In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario?

Authors:  Aida Ripoll; Fernando Baquero; Angela Novais; Mario J Rodríguez-Domínguez; Maria-Carmen Turrientes; Rafael Cantón; Juan-Carlos Galán
Journal:  Antimicrob Agents Chemother       Date:  2011-07-25       Impact factor: 5.191

Review 4.  Epidemiology of β-Lactamase-Producing Pathogens.

Authors:  Karen Bush; Patricia A Bradford
Journal:  Clin Microbiol Rev       Date:  2020-02-26       Impact factor: 26.132

5.  Crystal structure of a preacylation complex of the β-lactamase inhibitor sulbactam bound to a sulfenamide bond-containing thiol-β-lactamase.

Authors:  Elizabeth A Rodkey; Sarah M Drawz; Jared M Sampson; Christopher R Bethel; Robert A Bonomo; Focco van den Akker
Journal:  J Am Chem Soc       Date:  2012-09-26       Impact factor: 15.419

6.  Characterization of the inhibitor-resistant SHV β-lactamase SHV-107 in a clinical Klebsiella pneumoniae strain coproducing GES-7 enzyme.

Authors:  Vera Manageiro; Eugénia Ferreira; Antony Cougnoux; Luís Albuquerque; Manuela Caniça; Richard Bonnet
Journal:  Antimicrob Agents Chemother       Date:  2011-11-14       Impact factor: 5.191

7.  Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase.

Authors:  Marisa L Winkler; Elizabeth A Rodkey; Magdalena A Taracila; Sarah M Drawz; Christopher R Bethel; Krisztina M Papp-Wallace; Kerri M Smith; Yan Xu; Jeffrey R Dwulit-Smith; Chiara Romagnoli; Emilia Caselli; Fabio Prati; Focco van den Akker; Robert A Bonomo
Journal:  J Med Chem       Date:  2013-02-04       Impact factor: 7.446

8.  Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.

Authors:  Mei Li; Benjamin C Conklin; Magdalena A Taracila; Rebecca A Hutton; Marion J Skalweit
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

Review 9.  Three decades of beta-lactamase inhibitors.

Authors:  Sarah M Drawz; Robert A Bonomo
Journal:  Clin Microbiol Rev       Date:  2010-01       Impact factor: 26.132

Review 10.  Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.

Authors:  Mariana Castanheira; Patricia J Simner; Patricia A Bradford
Journal:  JAC Antimicrob Resist       Date:  2021-07-16
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