| Literature DB >> 18663019 |
Véronique Dubois1, Laurent Poirel, François Demarthe, Corinne Arpin, Laure Coulange, Luciene A R Minarini, Marie-Christine Bezian, Patrice Nordmann, Claudine Quentin.
Abstract
A clinical strain of Klebsiella pneumoniae was found to possess the chromosomal gene bla(SHV-56), encoding a new inhibitor-resistant beta-lactamase with a pI of 7.6. SHV-56 is derived from SHV-11 by the single substitution K234R. This mutation therefore evidences a new critical site for inhibitor resistance among SHV enzymes.Entities:
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Year: 2008 PMID: 18663019 PMCID: PMC2565901 DOI: 10.1128/AAC.00387-08
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191