Literature DB >> 18662537

SIRT1 is a circadian deacetylase for core clock components.

William J Belden1, Jay C Dunlap.   

Abstract

The transcriptional activator CLOCK is a histone acetyltransferase that is required for the circadian expression of many genes. Asher et al. (2008) and Nakahata et al. (2008) now demonstrate that the NAD(+)-dependent enzyme SIRT1 functions as a histone deacetylase that counteracts the activity of CLOCK. These results broaden our understanding of the impact of cellular metabolism on the circadian system.

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Year:  2008        PMID： 18662537      PMCID： PMC3671948          DOI： 10.1016/j.cell.2008.07.010

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  Light induces chromatin modification in cells of the mammalian circadian clock.

Authors:  C Crosio; N Cermakian; C D Allis; P Sassone-Corsi
Journal:  Nat Neurosci       Date:  2000-12       Impact factor: 24.884

2.  Rhythmic histone acetylation underlies transcription in the mammalian circadian clock.

Authors:  Jean-Pierre Etchegaray; Choogon Lee; Paul A Wade; Steven M Reppert
Journal:  Nature       Date:  2002-12-11       Impact factor: 49.962

Review 3.  The biochemistry of sirtuins.

Authors:  Anthony A Sauve; Cynthia Wolberger; Vern L Schramm; Jef D Boeke
Journal:  Annu Rev Biochem       Date:  2006       Impact factor: 23.643

4.  The polycomb group protein EZH2 is required for mammalian circadian clock function.

Authors:  Jean-Pierre Etchegaray; Xiaoming Yang; Jason P DeBruyne; Antoine H F M Peters; David R Weaver; Thomas Jenuwein; Steven M Reppert
Journal:  J Biol Chem       Date:  2006-05-22       Impact factor: 5.157

5.  Circadian regulator CLOCK is a histone acetyltransferase.

Authors:  Masao Doi; Jun Hirayama; Paolo Sassone-Corsi
Journal:  Cell       Date:  2006-05-05       Impact factor: 41.582

6.  The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control.

Authors:  Yasukazu Nakahata; Milota Kaluzova; Benedetto Grimaldi; Saurabh Sahar; Jun Hirayama; Danica Chen; Leonard P Guarente; Paolo Sassone-Corsi
Journal:  Cell       Date:  2008-07-25       Impact factor: 41.582

7.  CLOCK-mediated acetylation of BMAL1 controls circadian function.

Authors:  Jun Hirayama; Saurabh Sahar; Benedetto Grimaldi; Teruya Tamaru; Ken Takamatsu; Yasukazu Nakahata; Paolo Sassone-Corsi
Journal:  Nature       Date:  2007-12-13       Impact factor: 49.962

8.  Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions.

Authors:  Jürgen A Ripperger; Ueli Schibler
Journal:  Nat Genet       Date:  2006-02-12       Impact factor: 38.330

9.  Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.

Authors:  Anne M Curtis; Sang-beom Seo; Elizabeth J Westgate; Radu Daniel Rudic; Emer M Smyth; Debabrata Chakravarti; Garret A FitzGerald; Peter McNamara
Journal:  J Biol Chem       Date:  2003-11-26       Impact factor: 5.157
  9 in total
  52 in total

Review 1.  Regulation of SIRT1 in cellular functions: role of polyphenols.

Authors:  Sangwoon Chung; Hongwei Yao; Samuel Caito; Jae-Woong Hwang; Gnanapragasam Arunachalam; Irfan Rahman
Journal:  Arch Biochem Biophys       Date:  2010-05-05       Impact factor: 4.013

Review 2.  Circadian rhythms and cancer.

Authors:  Sigal Gery; H Philip Koeffler
Journal:  Cell Cycle       Date:  2010-03-15       Impact factor: 4.534

Review 3.  Circadian molecular clock in lung pathophysiology.

Authors:  Isaac K Sundar; Hongwei Yao; Michael T Sellix; Irfan Rahman
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2015-09-11       Impact factor: 5.464

4.  Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver.

Authors:  Serena Abbondante; Kristin L Eckel-Mahan; Nicholas J Ceglia; Pierre Baldi; Paolo Sassone-Corsi
Journal:  J Biol Chem       Date:  2015-12-07       Impact factor: 5.157

5.  Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.

Authors:  Jae-Woong Hwang; Isaac K Sundar; Hongwei Yao; Michael T Sellix; Irfan Rahman
Journal:  FASEB J       Date:  2013-09-11       Impact factor: 5.191

6.  Metabolism control by the circadian clock and vice versa.

Authors:  Kristin Eckel-Mahan; Paolo Sassone-Corsi
Journal:  Nat Struct Mol Biol       Date:  2009-05       Impact factor: 15.369

Review 7.  Circadian rhythms and memory: not so simple as cogs and gears.

Authors:  Kristin L Eckel-Mahan; Daniel R Storm
Journal:  EMBO Rep       Date:  2009-05-22       Impact factor: 8.807

8.  A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta.

Authors:  Tsuyoshi Hirota; Warren G Lewis; Andrew C Liu; Jae Wook Lee; Peter G Schultz; Steve A Kay
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-22       Impact factor: 11.205

9.  Circadian glucose homeostasis requires compensatory interference between brain and liver clocks.

Authors:  David Gatfield; Ueli Schibler
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-23       Impact factor: 11.205

Review 10.  Circadian redox rhythms in the regulation of neuronal excitability.

Authors:  Mia Y Bothwell; Martha U Gillette
Journal:  Free Radic Biol Med       Date:  2018-02-02       Impact factor: 7.376
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