Literature DB >> 18661300

Membrane proteins and squalene-hydrosqualene profile in methanoarchaeon Methanothermobacter thermautotrophicus resistant to N,N'-dicyclohexylcarbodiimide.

Z Nováková1, S Surín, J Blasko, A Majerník, P Smigán.   

Abstract

The biochemical basis of a defective bioenergetic system was attempted to be determined in N,N'-dicyclohexylcarbodiimide (DCCD)-resistant mutant of Methanothermobacter thermautotrophicus. Components participating in the maintenance of methanoarchaeal membrane structure and function, such as the composition of the mixture of squalene and its hydrosqualene derivatives and also properties of membrane-associated proteins were compared in wild-type and mutant cells. The impairment of the bioenergetic system in DCCD-resistant mutant was detectable in the membrane-protein profile; it was also accompanied by changes in proportions of squalene-hydrosqualenes.

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Year:  2008        PMID： 18661300     DOI： 10.1007/s12223-008-0034-x

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  15 in total

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Authors:  Volker Müller
Journal:  J Bioenerg Biomembr       Date:  2004-02       Impact factor: 2.945

2.  Isolation and characterization of an uncoupler-resistant mutant of Methanothermobacter thermautotrophicus.

Authors:  L'ubomíra Cubonová; Stanislav Surín; Alan Majerník; Peter Smigán
Journal:  FEMS Microbiol Lett       Date:  2004-04-01       Impact factor: 2.742

3.  Isolation and characterization of an amiloride-resistant mutant of Methanothermobacter thermautotrophicus possessing a defective Na+/H+ antiport.

Authors:  Stanislav Surín; L'ubomíra Cubonová; Alan I Majerník; Paul McDermott; James P J Chong; Peter Smigán
Journal:  FEMS Microbiol Lett       Date:  2007-02-05       Impact factor: 2.742

4.  The presence of H+ and Na(+)-translocating ATPases in Methanobacterium thermoautotrophicum and their possible function under alkaline conditions.

Authors:  P Smigán; A Majerník; P Polák; I Hapala; M Greksák
Journal:  FEBS Lett       Date:  1995-09-04       Impact factor: 4.124

5.  Isolation and characterization of a neomycin-resistant mutant of Methanobacterium thermoautotrophicum with a lesion in Na+-translocating ATPase (synthase).

Authors:  P Smigán; P Polák; A Majernik; M Greksák
Journal:  FEBS Lett       Date:  1997-12-22       Impact factor: 4.124

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Na(+)-driven ATP synthesis in Methanobacterium thermoautotrophicum and its differentiation from H(+)-driven ATP synthesis by rhodamine 6G.

Authors:  P Smigán; A Majerník; M Greksák
Journal:  FEBS Lett       Date:  1994-06-27       Impact factor: 4.124

8.  Extraction and composition of polar lipids from the archaebacterium, Methanobacterium thermoautotrophicum: effective extraction of tetraether lipids by an acidified solvent.

Authors:  M Nishihara; Y Koga
Journal:  J Biochem       Date:  1987-04       Impact factor: 3.387

9.  Delta mu Na+ drives the synthesis of ATP via an delta mu Na(+)-translocating F1F0-ATP synthase in membrane vesicles of the archaeon Methanosarcina mazei Gö1.

Authors:  B Becher; V Müller
Journal:  J Bacteriol       Date:  1994-05       Impact factor: 3.490

10.  Biochemical characteristics of a mutant of the methanoarchaeon Methanothermobacter thermautotrophicus resistant to the protonophoric uncoupler TCS.

Authors:  L Cijbonová; A Majerník; P Smigán
Journal:  Folia Microbiol (Praha)       Date:  2004       Impact factor: 2.099
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  2 in total

1.  Isolation and characterization of a N,N'-dicyclohexylcarbodiimide-resistant mutant of Methanothermobacter thermautotrophicus with alterations to the ATP synthesis machinery.

Authors:  Z Nováková; A I Majerník; J Bobál'ová; M Vidová; P Smigán
Journal:  Folia Microbiol (Praha)       Date:  2010-02-07       Impact factor: 2.099

2.  Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates.

Authors:  Nikki Dellas; Joseph P Noel
Journal:  ACS Chem Biol       Date:  2010-06-18       Impact factor: 5.100
  2 in total

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