Literature DB >> 18661126

Dual drug interactions via P-glycoprotein (P-gp)/ cytochrome P450 (CYP3A4) interplay: recent case study of oral atorvastatin and verapamil.

Nuggehally R Srinivas.   

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Year:  2008        PMID: 18661126     DOI: 10.1007/s00228-008-0512-8

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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  21 in total

1.  Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics.

Authors:  Scott W Grimm; Neil M Richtand; Helen R Winter; Karen R Stams; Stots B Reele
Journal:  Br J Clin Pharmacol       Date:  2006-01       Impact factor: 4.335

2.  The intestinal first-pass metabolism of substrates of CYP3A4 and P-glycoprotein-quantitative analysis based on information from the literature.

Authors:  Motohiro Kato; Koji Chiba; Akihiro Hisaka; Michi Ishigami; Makoto Kayama; Naomi Mizuno; Yoshinori Nagata; Susumu Takakuwa; Yuko Tsukamoto; Kaoru Ueda; Hiroyuki Kusuhara; Kiyomi Ito; Yuichi Sugiyama
Journal:  Drug Metab Pharmacokinet       Date:  2003       Impact factor: 3.614

3.  Validation of the hepatic blood flow rate model for verapamil first-pass metabolism.

Authors:  Jovan Popović
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2007 Jan-Mar       Impact factor: 2.441

Review 4.  Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption.

Authors:  Joseph M Custodio; Chi-Yuan Wu; Leslie Z Benet
Journal:  Adv Drug Deliv Rev       Date:  2007-11-28       Impact factor: 15.470

Review 5.  Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.

Authors:  Pertti J Neuvonen; Mikko Niemi; Janne T Backman
Journal:  Clin Pharmacol Ther       Date:  2006-12       Impact factor: 6.875

6.  Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

Authors:  Elke S Perloff; Su X Duan; Paul R Skolnik; David J Greenblatt; Lisa L von Moltke
Journal:  Drug Metab Dispos       Date:  2005-03-11       Impact factor: 3.922

7.  Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4.

Authors:  J H Hochman; M Chiba; J Nishime; M Yamazaki; J H Lin
Journal:  J Pharmacol Exp Ther       Date:  2000-01       Impact factor: 4.030

Review 8.  Lessons learned from the irinotecan metabolic pathway.

Authors:  M K Ma; H L McLeod
Journal:  Curr Med Chem       Date:  2003-01       Impact factor: 4.530

9.  An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constituents.

Authors:  Amy S Etheridge; Sherry R Black; Purvi R Patel; James So; James M Mathews
Journal:  Planta Med       Date:  2007-07-05       Impact factor: 3.352

Review 10.  Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.

Authors:  L Z Benet; C L Cummins; C Y Wu
Journal:  Curr Drug Metab       Date:  2003-10       Impact factor: 3.731

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  2 in total

1.  Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism.

Authors:  Deep Kwatra; Balasubramanyam Budda; Aswani Dutt Vadlapudi; Ramya Krishna Vadlapatla; Dhananjay Pal; Ashim K Mitra
Journal:  Mol Pharm       Date:  2012-06-19       Impact factor: 4.939

2.  Effect of verapamil on the pharmacokinetics of hydroxycamptothecin and its potential mechanism.

Authors:  Hua Xing; Xiao Luo; Yang Li; Chunni Fan; Ning Liu; Chunguo Cui; Wenjia Li
Journal:  Pharm Biol       Date:  2020-12       Impact factor: 3.503

  2 in total

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