Age-dependent discrepancies between computerized and paper cognitive testing in patients with schizophrenia.

Computer-based cognitive testing is gaining in popularity because of desirable features such as ease of use, standardized administration and online data acquisition. Information technology and computer familiarity are clearly influenced by age in the general population, but the impact of this situation on cognitive testing of patients with schizophrenia has received little attention. In the present paper, participants underwent cognitive testing with computer and paper versions of the same tests. Patients underperformed controls by 1.36 DS (paper tests) and 2.27 DS (computer tests) after controlling for education. Results were highly correlated but patients with schizophrenia were disproportionately impaired on computer tests compared with their paper counterparts. Moreover, for subtests implying active keyboard input from the participant, the difference between paper and computer scores correlated with age in patients, a pattern that was not found in controls. These results have methodological implications because of the implied risk of measuring (lack of) computer proficiency in addition to bona fide cognitive deficits. They confirm, moreover, that patients with schizophrenia are victims of the "digital divide", which adds to the potential benefits of approaches like computer assisted cognitive remediation in this population.