Literature DB >> 18656986

Bioactive brominated metabolites from the red sea sponge Suberea mollis.

Mohamed I Abou-Shoer1, Lamiaa A Shaala, Diaa T A Youssef, Jihan M Badr, Abdel-Azim M Habib.   

Abstract

Reinvestigation of the Red Sea sponge Suberea mollis afforded two new bromotyrosine-derived alkaloids, subereamollines A (1) and B (2), two new brominated phenolic compounds, subereaphenols B (7) and C (9), and the known compounds aerothionin (3), homoaerothionin (4), 11,19-dideoxyfistularin-3 (5), aeroplysinin-1 (6), and aeroplysinin-2 (8). The structure determination of the isolated compounds was assigned using one- and two-dimensional NMR spectra and HRFABMS data. The antimicrobial and antioxidant activities of the isolated compounds have been evaluated. Aeroplysinin-1 displayed significant antimicrobial activity against S. aureus, P. aerugenosa, and K. pneumoniae. The isolated compounds were examined for their antioxidant activity using a 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) solution-based chemical assay. Among the tested compounds, only subereaphenols B and C displayed a significant effect.

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Year:  2008        PMID： 18656986     DOI： 10.1021/np800142n

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  19 in total

Review 1.  Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.

Authors:  Takashi L Suyama; William H Gerwick; Kerry L McPhail
Journal:  Bioorg Med Chem       Date:  2011-06-12       Impact factor: 3.641

2.  A Model Study toward the Concise Synthesis of Bromotyrosine Derived Spiroisoxazoline Natural Products and Analogous Core Structures.

Authors:  Prasanta Das; Edward J Valente; Ashton T Hamme
Journal:  European J Org Chem       Date:  2014-05-01

3.  Bioactive secondary metabolites from the Red Sea marine Verongid sponge Suberea species.

Authors:  Lamiaa A Shaala; Diaa T A Youssef; Jihan M Badr; Mansour Sulaiman; Alaa Khedr
Journal:  Mar Drugs       Date:  2015-03-24       Impact factor: 5.118

4.  Bioactive Bromotyrosine-Derived Alkaloids from the Polynesian Sponge Suberea ianthelliformis.

Authors:  Amr El-Demerdash; Céline Moriou; Jordan Toullec; Marc Besson; Stéphanie Soulet; Nelly Schmitt; Sylvain Petek; David Lecchini; Cécile Debitus; Ali Al-Mourabit
Journal:  Mar Drugs       Date:  2018-04-27       Impact factor: 5.118

5.  New Source of 3D Chitin Scaffolds: The Red Sea Demosponge Pseudoceratina arabica (Pseudoceratinidae, Verongiida).

Authors:  Lamiaa A Shaala; Hani Z Asfour; Diaa T A Youssef; Sonia Żółtowska-Aksamitowska; Marcin Wysokowski; Mikhail Tsurkan; Roberta Galli; Heike Meissner; Iaroslav Petrenko; Konstantin Tabachnick; Viatcheslav N Ivanenko; Nicole Bechmann; Lyubov V Muzychka; Oleg B Smolii; Rajko Martinović; Yvonne Joseph; Teofil Jesionowski; Hermann Ehrlich
Journal:  Mar Drugs       Date:  2019-02-01       Impact factor: 5.118

6.  Antiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina sp.

Authors:  Nicolas Lebouvier; Valérie Jullian; Isabelle Desvignes; Séverine Maurel; Arnaud Parenty; Dominique Dorin-Semblat; Christian Doerig; Michel Sauvain; Dominique Laurent
Journal:  Mar Drugs       Date:  2009-11-23       Impact factor: 5.118

7.  Subereamolline A as a potent breast cancer migration, invasion and proliferation inhibitor and bioactive dibrominated alkaloids from the Red Sea sponge Pseudoceratina arabica.

Authors:  Lamiaa A Shaala; Diaa T A Youssef; Mansour Sulaiman; Fathy A Behery; Ahmed I Foudah; Khalid A El Sayed
Journal:  Mar Drugs       Date:  2012-11-08       Impact factor: 5.118

8.  Bromotyrosine-derived alkaloids from the Caribbean sponge Aplysina lacunosa.

Authors:  Qun Göthel; Thanchanok Sirirak; Matthias Köck
Journal:  Beilstein J Org Chem       Date:  2015-11-26       Impact factor: 2.883

9.  Red Sea Suberea mollis Sponge Extract Protects against CCl4-Induced Acute Liver Injury in Rats via an Antioxidant Mechanism.

Authors:  Aymn T Abbas; Nagla A El-Shitany; Lamiaa A Shaala; Soad S Ali; Esam I Azhar; Umama A Abdel-Dayem; Diaa T A Youssef
Journal:  Evid Based Complement Alternat Med       Date:  2014-08-19       Impact factor: 2.629

Review 10.  Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates.

Authors:  Claudio Luparello; Manuela Mauro; Valentina Lazzara; Mirella Vazzana
Journal:  Molecules       Date:  2020-05-26       Impact factor: 4.411
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