| Literature DB >> 18656983 |
Abstract
A highly chemoselective reduction of aromatic nitro compounds to the corresponding amino derivatives has been achieved by a combination of copper nanoparticles and ammonium formate in ethylene glycol at 120 degrees C. The reductions are successfully carried out in presence of a wide variety of other reducible functional groups in the molecule, such as Cl, I, OCH2Ph, NHCH2Ph, COR, COOR, CN, etc. The reactions are very clean and high yielding.Entities:
Year: 2008 PMID： 18656983 DOI： 10.1021/jo800863m
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354