| Literature DB >> 18656351 |
Jian-Chiou Su1, Chin-Lu Tseng, Ting-Gung Chang, Wen-Jen Yu, Shih-Kwang Wu.
Abstract
A solid phase synthesis method was established for the synthesis of peptide-poly(ethylene glycol)-lipid (peptide-PEG-lipid) conjugates. Octreotide-PEG(2000)-DSPE (OPD(2000)) was used as an example to demonstrate the synthetic approach. The OPD(2000) obtained had confirmed structure, activity, and purity providing a targeting molecule for preparation of well-defined drug delivery systems, such as targeted liposomes, for further studies.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18656351 DOI： 10.1016/j.bmcl.2008.07.027
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823