| Literature DB >> 18653995 |
Yasuhiro Kojima1, Toshiaki Sunazuka, Kenichiro Nagai, Khachatur Julfakyan, Takashi Fukuda, Hiroshi Tomoda, Satoshi Omura.
Abstract
Total synthesis of a fungal cyclic peptide, malformin C, recently rediscovered as a G2 checkpoint inhibitor was completed. Our synthesis involved a convergent approach with respect to a linear pentapeptide, cyclization, and oxidative disulfide formation.Entities:
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Year: 2008 PMID： 18653995 DOI： 10.1038/ja.2008.42
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649