Literature DB >> 1865212

Contractile properties of lower leg muscles are normal in Parkinson's disease.

A Hufschmidt1, K Stark, C H Lücking.   

Abstract

Contraction parameters (time-to-peak and half relaxation time), responses to short tetani and resistance to stretch were studied in the lower leg muscles of Parkinsonian patients and in age-matched controls. It was possible to distinguish between muscle groups of different fibre type composition in normal subjects on the basis of their contraction and relaxation velocities. These parameters, however, failed to show any abnormalities in the patient group. The only abnormal finding in Parkinsonian subjects was an increased resistance to passive stretch under static conditions, presumably elastic in origin. The results are evidence against a contribution of altered contractile properties to muscular rigidity in Parkinsonism.

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Year:  1991        PMID: 1865212      PMCID: PMC488550          DOI: 10.1136/jnnp.54.5.457

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  21 in total

1.  Dynamic properties of fast and slow skeletal muscles in the cat and rat following cross-reinnervation.

Authors:  A R Luff
Journal:  J Physiol       Date:  1975-06       Impact factor: 5.182

2.  Ultrastructure of skeletal muscle in patients with Parkinson's disease and upper motor lesions.

Authors:  G Ahlqvist; S Landin; R Wroblewski
Journal:  Lab Invest       Date:  1975-05       Impact factor: 5.662

3.  Evidence for abnormal long-loop reflexes in rigid Parkinsonian patients.

Authors:  W G Tatton; R G Lee
Journal:  Brain Res       Date:  1975-12-26       Impact factor: 3.252

4.  Time dependent effects on contractile properties, fibre population, myosin light chains and enzymes of energy metabolism in intermittently and continuously stimulated fast twitch muscles of the rabbit.

Authors:  D Pette; W Müller; E Leisner; G Vrbová
Journal:  Pflugers Arch       Date:  1976-07-30       Impact factor: 3.657

5.  The response to muscle stretch and shortening in Parkinsonian rigidity.

Authors:  C J Andrews; D Burke; J W Lance
Journal:  Brain       Date:  1972       Impact factor: 13.501

6.  Effects of long-term electrical stimulation on some contractile and metabolic characteristics of fast rabbit muscles.

Authors:  D Pette; M E Smith; H W Staudte; G Vrbová
Journal:  Pflugers Arch       Date:  1973-02-06       Impact factor: 3.657

7.  Polysynaptic spinal reflexes in Parkinson's disease.

Authors:  P J Delwaide; R S Schwab; R R Young
Journal:  Neurology       Date:  1974-09       Impact factor: 9.910

8.  Contraction times and fibre types in intact human muscle.

Authors:  F Buchthal; H Schmalbruch
Journal:  Acta Physiol Scand       Date:  1970-08

9.  Dynamic properties of fast and slow skeletal muscles of the rat after nerve cross-union.

Authors:  R Close
Journal:  J Physiol       Date:  1969-10       Impact factor: 5.182

10.  Contractile properties of muscle: control by pattern of muscle activity in the rat.

Authors:  T Lomo; R H Westgaard; H A Dahl
Journal:  Proc R Soc Lond B Biol Sci       Date:  1974-08-27
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