| Literature DB >> 1865211 |
C E Clarke1, D I Shepherd, G M Yuill, J C Smaje, P B Wilson.
Abstract
In a retrospective case note study of 86 patients with myasthenia gravis, 60 had an anti-acetylcholine receptor antibody assay performed by the regional immunology laboratory. Antibody was detected in 38% which compares with 66-93% in other series. Whilst the use of staphylococcal protein A to precipitate the antibody-receptor complex, rather than anti-human immunoglobulin, may be partly responsible for this low sensitivity, other methodological problems are likely to exist. It is suggested that this potentially critical assay becomes a subject for regular audit.Entities:
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Year: 1991 PMID： 1865211 PMCID： PMC488549 DOI： 10.1136/jnnp.54.5.454
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154