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Literature DB >> 1865206

Glial swelling following human cerebral contusion: an ultrastructural study.

R Bullock¹, W L Maxwell, D I Graham, G M Teasdale, J H Adams.

Abstract

The ultrastructural features of cerebral contusion seen three hours to 11 days after head injury were studied in 18 patients undergoing surgery. Massive astrocytic swelling ("cytotoxic" oedema) was seen three hours to three days after injury, maximal in perivascular foot processes, and compressing some of the underlying capillaries. The tight junctions were not disrupted. Neuronal damage was most marked three to 11 days after injury. The pathophysiological mechanisms leading to oedema formation and neuronal degeneration are discussed.

Entities: Disease Species

Mesh：

Year: 1991 PMID： 1865206 PMCID： PMC488543 DOI： 10.1136/jnnp.54.5.427

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

18 in total

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34 in total

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Review 3. Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress.

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Authors: Jaclynn Levine; Eunice Kwon; Pablo Paez; Weihong Yan; Gregg Czerwieniec; Joseph A Loo; Michael V Sofroniew; Ina-Beate Wanner
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Journal: Brain Res Date: 2014-06-13 Impact factor: 3.252

10. Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation.

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Journal: J Neurosci Date: 2009-06-17 Impact factor: 6.167