| Literature DB >> 18651734 |
Johannes Pall Magnusson1, Adnan Khan, George Pasparakis, Aram Omer Saeed, Wenxin Wang, Cameron Alexander.
Abstract
Ion-sensitive responsive polymers are prepared under fully aqueous conditions using controlled radical polymerization. Variations in comonomer content and sequence lead to temperature and salt-dependent solution behavior, with cloud-points ranging by +/-40 degrees C following addition of Hofmeister series salts. A "hybrid" block copolymer, composed of a statistical sequence of monomers tipped with a hydrophilic block, formed stable micelle-like assemblies that exhibited burst release of an encapsulated model drug in response to addition of a kosmotrope, Na2SO4, at room temperature.Entities:
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Year: 2008 PMID： 18651734 DOI： 10.1021/ja802609r
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419