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Literature DB >> 1865033

Wegener's granulomatosis presenting as diffuse pulmonary hemorrhage.

B Misset¹, D Glotz, B Escudier, D Nochy, J Bosq, E Gilles, B Leclercq, G Nitenberg.

Abstract

A 35-year-old woman experienced diffuse intraalveolar haemorrhage with respiratory distress and acute renal failure. Renal histology and evolution confirmed Wegener's granulomatosis. Early use of immunosuppressive drugs allowed weaning from mechanical ventilation and temporary improvement of the renal failure. A review of the literature emphasizes the rarity of alveolar hemorrhage as an initial symptom of Wegener's granulomatosis and the necessity of aggressive management.

Entities: Disease Species

Mesh：

Year: 1991 PMID： 1865033 DOI： 10.1007/bf01691435

Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440

11 in total

1. Idiopathic pulmonary hemosiderosis with manifestations of multiple connective tissue and immune disorders. Treatment with cyclophosphamide.

Authors: W J O'Donohue
Journal: Am Rev Respir Dis Date: 1974-04

2. Lymphomatoid granulomatosis.

Authors: A A Liebow; C R Carrington; P J Friedman
Journal: Hum Pathol Date: 1972-12 Impact factor: 3.466

Review 3. Immune alveolar hemorrhage.

Authors: J W Leatherman
Journal: Chest Date: 1987-06 Impact factor: 9.410

4. Acute fulminating intrapulmonary haemorrhage in Wegener's granulomatosis.

Authors: T C Stokes; B G McCann; R T Rees; E H Sims; B D Harrison
Journal: Thorax Date: 1982-04 Impact factor: 9.139

5. Diffuse pulmonary hemorrhage and rapidly progressive renal failure. An uncommon presentation of Wegener's granulomatosis.

Authors: M J Hensley; N T Feldman; J M Lazarus; E G Galvanek
Journal: Am J Med Date: 1979-05 Impact factor: 4.965

1. A case of Wegener's granulomatosis complicated by diffuse pulmonary hemorrhage and thrombotic thrombocytopenic purpura.

Authors: H E Lim; S K Jo; S W Kim; H K Choi; I B Suh; S Y Yoon; J S Moon; N H Won; Y J Kwon; H J Pyo
Journal: Korean J Intern Med Date: 1998-02 Impact factor: 2.884

1 in total

Wegener's granulomatosis presenting as diffuse pulmonary hemorrhage.

1. Idiopathic pulmonary hemosiderosis with manifestations of multiple connective tissue and immune disorders. Treatment with cyclophosphamide.

2. Lymphomatoid granulomatosis.

Review 3. Immune alveolar hemorrhage.

4. Acute fulminating intrapulmonary haemorrhage in Wegener's granulomatosis.

5. Diffuse pulmonary hemorrhage and rapidly progressive renal failure. An uncommon presentation of Wegener's granulomatosis.

6. Diffuse intrapulmonary hemorrhage and glomerulonephritis unrelated to anti-glomerular basement membrane antibody.

7. Role of bronchoalveolar lavage in the assessment of opportunistic pulmonary infections: utility and complications.

8. Diagnosis of pulmonary hemorrhage in the immunocompromised host.

9. Renal biopsy pathology in Wegener's granulomatosis.

Review 10. Alveolar hemorrhage syndromes: diffuse microvascular lung hemorrhage in immune and idiopathic disorders.

1. A case of Wegener's granulomatosis complicated by diffuse pulmonary hemorrhage and thrombotic thrombocytopenic purpura.