Literature DB >> 18648766

Resource utilisation and costs associated with the treatment of diabetic foot ulcers. Prospective data from the Eurodiale Study.

L Prompers1, M Huijberts, N Schaper, J Apelqvist, K Bakker, M Edmonds, P Holstein, E Jude, A Jirkovska, D Mauricio, A Piaggesi, H Reike, M Spraul, K Van Acker, S Van Baal, F Van Merode, L Uccioli, V Urbancic, G Ragnarson Tennvall.   

Abstract

AIMS/HYPOTHESIS: The aim of the present study was to investigate resource utilisation and associated costs in patients with diabetic foot ulcers and to analyse differences in resource utilisation between individuals with or without peripheral arterial disease (PAD) and/or infection.
METHODS: Data on resource utilisation were collected prospectively in a European multicentre study. Data on 1,088 patients were available for the analysis of resource use, and data on 821 patients were included in the costing analysis. Costs were calculated for each patient by multiplying the country-specific direct and indirect unit costs by the number of resources used from inclusion into the study up to a defined endpoint. Country-specific costs were converted into purchasing power standards.
RESULTS: Resource use and costs varied between outcome groups and between disease severity groups. The highest costs per patient were for hospitalisation, antibiotics, amputations and other surgery. All types of resource utilisation and costs increased with the severity of disease. The total cost per patient was more than four times higher for patients with infection and PAD at inclusion than for patients in the least severe group, who had neither. CONCLUSIONS/
INTERPRETATION: Important differences in resource use and costs were found between different patient groups. The costs are highest for individuals with both peripheral arterial disease and infection, and these are mainly related to substantial costs for hospitalisation. In view of the magnitude of the costs associated with in-hospital stay, reducing the number and duration of hospital admissions seems an attractive option to decrease costs in diabetic foot disease.

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Year:  2008        PMID: 18648766     DOI: 10.1007/s00125-008-1089-6

Source DB:  PubMed          Journal:  Diabetologia        ISSN: 0012-186X            Impact factor:   10.122


  19 in total

Review 1.  Wound healing in diabetes. Outcome and costs.

Authors:  J Apelqvist
Journal:  Clin Podiatr Med Surg       Date:  1998-01       Impact factor: 1.231

2.  Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes Study.

Authors:  W A Davis; P E Norman; D G Bruce; T M E Davis
Journal:  Diabetologia       Date:  2006-09-26       Impact factor: 10.122

3.  High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study.

Authors:  L Prompers; M Huijberts; J Apelqvist; E Jude; A Piaggesi; K Bakker; M Edmonds; P Holstein; A Jirkovska; D Mauricio; G Ragnarson Tennvall; H Reike; M Spraul; L Uccioli; V Urbancic; K Van Acker; J van Baal; F van Merode; N Schaper
Journal:  Diabetologia       Date:  2006-11-09       Impact factor: 10.122

4.  Costs of lower-extremity ulcers among patients with diabetes.

Authors:  Karen Stockl; Ann Vanderplas; Eskinder Tafesse; Eunice Chang
Journal:  Diabetes Care       Date:  2004-09       Impact factor: 19.112

5.  Long-term costs for foot ulcers in diabetic patients in a multidisciplinary setting.

Authors:  J Apelqvist; G Ragnarson-Tennvall; J Larsson; U Persson
Journal:  Foot Ankle Int       Date:  1995-07       Impact factor: 2.827

6.  Health-economic consequences of diabetic foot lesions.

Authors:  Gunnel Ragnarson Tennvall; Jan Apelqvist
Journal:  Clin Infect Dis       Date:  2004-08-01       Impact factor: 9.079

7.  An economic evaluation of the cost of diabetic foot ulcers: results of a retrospective study on 239 patients.

Authors:  I Girod; P Valensi; C Laforêt; T Moreau-Defarges; P Guillon; F Baron
Journal:  Diabetes Metab       Date:  2003-06       Impact factor: 6.041

8.  The cost of managing diabetic foot ulceration in an Irish hospital.

Authors:  D Smith; M J Cullen; J J Nolan
Journal:  Ir J Med Sci       Date:  2004 Apr-Jun       Impact factor: 1.568

9.  Optimal organization of health care in diabetic foot disease: introduction to the Eurodiale study.

Authors:  Leonne Prompers; Maya Huijberts; Jan Apelqvist; Edward Jude; Alberto Piaggesi; Karel Bakker; Michael Edmonds; Per Holstein; Alexandra Jirkovska; Didac Mauricio; Gunnel Ragnarson Tennvall; Heinrich Reike; Maximilian Spraul; Luigi Uccioli; Vilma Urbancic; Kristien Van Acker; Jeff Van Baal; Frits Van Merode; Nicolaas Schaper
Journal:  Int J Low Extrem Wounds       Date:  2007-03       Impact factor: 2.057

10.  Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study.

Authors:  L Prompers; N Schaper; J Apelqvist; M Edmonds; E Jude; D Mauricio; L Uccioli; V Urbancic; K Bakker; P Holstein; A Jirkovska; A Piaggesi; G Ragnarson-Tennvall; H Reike; M Spraul; K Van Acker; J Van Baal; F Van Merode; I Ferreira; M Huijberts
Journal:  Diabetologia       Date:  2008-02-23       Impact factor: 10.122

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  59 in total

1.  The major predictors of amputation and length of stay in diabetic patients with acute foot ulceration.

Authors:  Suzan Tabur; Mehmet Ali Eren; Yakup Çelik; Omer Faruk Dağ; Tevfik Sabuncu; Zeynel Abidin Sayiner; Esen Savas
Journal:  Wien Klin Wochenschr       Date:  2014-11-15       Impact factor: 1.704

Review 2.  Diabetic foot disease in people with advanced nephropathy and those on renal dialysis.

Authors:  Agbor Ndip; Lawrence A Lavery; Andrew J M Boulton
Journal:  Curr Diab Rep       Date:  2010-08       Impact factor: 4.810

3.  Ulcer-free survival days and ulcer healing in patients with diabetic foot ulcers: A prospective cohort study.

Authors:  Afram Akturk; Jaap J van Netten; Rene Scheer; Marloes Vermeer; Jeff G van Baal
Journal:  Int Wound J       Date:  2019-08-19       Impact factor: 3.315

Review 4.  Diabetic foot infections: microbiological aspects, current and future antibiotic therapy focusing on methicillin-resistant Staphylococcus aureus.

Authors:  Andreas Ambrosch; Simone Haefner; Edward Jude; Ralf Lobmann
Journal:  Int Wound J       Date:  2011-08-23       Impact factor: 3.315

5.  Prevalence and healthcare costs associated with the management of diabetic foot ulcer in patients attending Ahmadu Bello University Teaching Hospital, Nigeria.

Authors:  Umar Mukhtar Danmusa; Iorliam Terhile; Idris Abdullahi Nasir; Auwal Alkasim Ahmad; Habiba Yahaya Muhammad
Journal:  Int J Health Sci (Qassim)       Date:  2016-04

Review 6.  Infected animal models for tissue engineering.

Authors:  Alexander M Tatara; Sarita R Shah; Carissa E Livingston; Antonios G Mikos
Journal:  Methods       Date:  2015-04-02       Impact factor: 3.608

Review 7.  New Molecular Techniques to Study the Skin Microbiota of Diabetic Foot Ulcers.

Authors:  Jean-Philippe Lavigne; Albert Sotto; Catherine Dunyach-Remy; Benjamin A Lipsky
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-01-01       Impact factor: 4.730

8.  Cell therapy, a new standard in management of chronic critical limb ischemia and foot ulcer.

Authors:  V Procházka; J Gumulec; F Jalůvka; D Salounová; T Jonszta; D Czerný; J Krajča; R Urbanec; P Klement; J Martinek; G L Klement
Journal:  Cell Transplant       Date:  2010-06-07       Impact factor: 4.064

Review 9.  Cost of diabetic eye, renal and foot complications: a methodological review.

Authors:  Solène Schirr-Bonnans; Nadège Costa; Hélène Derumeaux-Burel; Jérémy Bos; Benoît Lepage; Valérie Garnault; Jacques Martini; Hélène Hanaire; Marie-Christine Turnin; Laurent Molinier
Journal:  Eur J Health Econ       Date:  2016-03-14

10.  [Diabetic foot syndrome from the perspective of angiology and diabetology].

Authors:  H Lawall; C Diehm
Journal:  Orthopade       Date:  2009-12       Impact factor: 1.087

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