Literature DB >> 18647461

Decentralised management of drug-resistant tuberculosis (MDR- and XDR-TB) in South Africa: an alternative model of care.

N Padayatchi1, G Friedland.   

Abstract

SETTING: A growing number of cases of extensively drug-resistant tuberculosis (XDR-TB) have been reported from KwaZulu-Natal, South Africa.
OBJECTIVE: To propose an alternative model to centralised care that can be implemented to alleviate the current emergency. DISCUSSION: The current failing TB programme could be improved by borrowing strategies such as decentralisation of care, treatment expertise, high levels of treatment adherence and successful outcomes, all of which have been successfully implemented in the human immunodeficiency virus programme. Patients with multidrug-resistant or XDR-TB could be admitted to institutions closer to their homes for treatment with subsequent discharge to home-based care.
CONCLUSION: The longer we support a failed system or wait for a perfect solution, the more the current devastation will continue to grow.

Entities:  

Mesh:

Year:  2008        PMID: 18647461

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  15 in total

1.  Averting epidemics of extensively drug-resistant tuberculosis.

Authors:  Sanjay Basu; Gerald H Friedland; Jan Medlock; Jason R Andrews; N Sarita Shah; Neel R Gandhi; Anthony Moll; Prashini Moodley; A Willem Sturm; Alison P Galvani
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-13       Impact factor: 11.205

2.  High treatment failure and default rates for patients with multidrug-resistant tuberculosis in KwaZulu-Natal, South Africa, 2000-2003.

Authors:  J C M Brust; N R Gandhi; H Carrara; G Osburn; N Padayatchi
Journal:  Int J Tuberc Lung Dis       Date:  2010-04       Impact factor: 2.373

3.  Comparing early treatment outcomes of MDR-TB in decentralised and centralised settings in KwaZulu-Natal, South Africa.

Authors:  M Loveday; K Wallengren; A Voce; B Margot; T Reddy; I Master; J Brust; K Chaiyachati; N Padayatchi
Journal:  Int J Tuberc Lung Dis       Date:  2012-02       Impact factor: 2.373

4.  Impact of reduced hospitalisation on the cost of treatment for drug-resistant tuberculosis in South Africa.

Authors:  E Sinanovic; L Ramma; A Vassall; V Azevedo; L Wilkinson; N Ndjeka; K McCarthy; G Churchyard; H Cox
Journal:  Int J Tuberc Lung Dis       Date:  2015-02       Impact factor: 2.373

Review 5.  Nano/Microfluidics for diagnosis of infectious diseases in developing countries.

Authors:  Won Gu Lee; Yun-Gon Kim; Bong Geun Chung; Utkan Demirci; Ali Khademhosseini
Journal:  Adv Drug Deliv Rev       Date:  2009-11-30       Impact factor: 15.470

Review 6.  Multidrug-resistant and extensively drug-resistant tuberculosis: consequences for the global HIV community.

Authors:  Sheela Shenoi; Scott Heysell; Anthony Moll; Gerald Friedland
Journal:  Curr Opin Infect Dis       Date:  2009-02       Impact factor: 4.915

Review 7.  Extensively drug-resistant tuberculosis: a new face to an old pathogen.

Authors:  Sheela Shenoi; Gerald Friedland
Journal:  Annu Rev Med       Date:  2009       Impact factor: 13.739

8.  Infection Control for Drug-Resistant Tuberculosis: Early Diagnosis and Treatment Is the Key.

Authors:  Gilles van Cutsem; Petros Isaakidis; Jason Farley; Ed Nardell; Grigory Volchenkov; Helen Cox
Journal:  Clin Infect Dis       Date:  2016-05-15       Impact factor: 9.079

9.  Rifampicin-Carbohydrate Spray-Dried Nanocomposite: A Futuristic Multiparticulate Platform For Pulmonary Delivery.

Authors:  Mohammed M Mehanna; Salma M Mohyeldin; Nazik A Elgindy
Journal:  Int J Nanomedicine       Date:  2019-11-22

10.  Treatment outcomes of multidrug-resistant tuberculosis patients in Gauteng, South Africa.

Authors:  E Marais; C K Mlambo; J J Lewis; N Rastogi; T Zozio; M P Grobusch; A Duse; T Victor; R W Warren
Journal:  Infection       Date:  2013-12-21       Impact factor: 3.553

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