| Literature DB >> 18646863 |
Steven R Angle1, Inchang Choi, Fook S Tham.
Abstract
A formal [3 + 2]-cycloaddition involving the Lewis acid mediated reaction of alpha-silyloxy aldehydes and styrenes to afford 3-alkyl-2-aryltetrahydrofuran-4-ols has been developed. This methodology was applied to the total synthesis of the naturally occurring furofuran lignan (+/-)-paulownin.Entities:
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Year: 2008 PMID： 18646863 DOI： 10.1021/jo800901r
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354