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Literature DB >> 1864508

Characterization of CARE-1: Candida albicans repetitive element-1.

B A Lasker¹, L S Page, T J Lott, G S Kobayashi, G Medoff.

Abstract

A middle repetitive DNA element, Candida albicans repetitive element-1 (CARE-1) has been isolated from the pathogenic yeast C. albicans. CARE-1 appears to be species-specific and constitutes approx. 0.045% of total C. albicans DNA, or a reiteration frequency of about two to twelve copies per haploid genome. The CARE-1 element has been detected on several C. albicans chromosomes separated by field-inversion gel electrophoresis, suggesting that the element is dispersed. Interstrain variation was observed in the number and distribution of hybridizing bands. The element is well conserved, since no nucleotide (nt) heterogeneity was observed when the sequences of two CARE-1 family members isolated from two different chromosomes (A and B) of C. albicans were compared. CARE-1 possesses 467 bp and is characterized by several stretches of A's and T's, short direct repeats and shows no significant homology to any known nt sequence.

Entities: Species

Mesh：

Substances：
DNA, Fungal

Year: 1991 PMID： 1864508 DOI： 10.1016/0378-1119(91)90536-k

Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688

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Cited

9 in total

1. Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination.

Authors: Y Gräser; M Volovsek; J Arrington; G Schönian; W Presber; T G Mitchell; R Vilgalys
Journal: Proc Natl Acad Sci U S A Date: 1996-10-29 Impact factor: 11.205

9. Identification to the species level and differentiation between strains of Aspergillus clinical isolates by automated repetitive-sequence-based PCR.

Authors: M Healy; K Reece; D Walton; J Huong; K Shah; D P Kontoyiannis
Journal: J Clin Microbiol Date: 2004-09 Impact factor: 5.948

9 in total

Characterization of CARE-1: Candida albicans repetitive element-1.

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