Literature DB >> 18644210

Characterization of autopsy-proven fatal asthma patients in São Paulo, Brazil.

Thais Mauad1, Diogenes S Ferreira, Maria Beatriz G Costa, Bianca B Araujo, Luiz Fernando F Silva, Milton A Martins, Sally E Wenzel, Marisa Dolhnikoff.   

Abstract

Few data are available on autopsy-proven fatal asthma patients in São Paulo, Brazil. We characterized 73 asthma patients who were autopsied at the Serviço de Verificação de Obitos da Universidade de São Paulo between 1996 and 2004. An interview with the next of kin assessed socioeconomic status, history, and treatment of asthma. There were 42 women and 31 men. Fifty-six (76.7%) of them were older than 34 years. Sixty-three percent were Caucasians, 77.3% had < 8 years of schooling, and the median income was 1.6 times the minimum wage. Twenty-two patients (30.1%) were smokers and 14 (19.2%) were ex-smokers. Only 25 (34.2%) patients were regularly followed by a doctor. Only 12.3% received inhaled steroids. Thirty-five patients (47.9%) had moderate-to-severe asthma. Fifty-five (75.3%) deaths took place outside a hospital. We conclude that this population shares characteristics of severe or poorly controlled asthma, low educational and socioeconomic levels, and lack of medical care and of inhaled steroid use.

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Year:  2008        PMID: 18644210     DOI: 10.1590/s1020-49892008000600007

Source DB:  PubMed          Journal:  Rev Panam Salud Publica        ISSN: 1020-4989


  3 in total

1.  Structural alterations and markers of endothelial activation in pulmonary and bronchial arteries in fatal asthma.

Authors:  Renata Calciolari Rossi; Raquel Anonni; Diogenes Seraphim Ferreira; Luiz Fernando Ferraz da Silva; Thais Mauad
Journal:  Allergy Asthma Clin Immunol       Date:  2019-08-28       Impact factor: 3.406

2.  Effects of Anti-IL-17 on Inflammation, Remodeling, and Oxidative Stress in an Experimental Model of Asthma Exacerbated by LPS.

Authors:  Leandro do Nascimento Camargo; Renato Fraga Righetti; Luciana Ritha de Cássia Rolim Barbosa Aristóteles; Tabata Maruyama Dos Santos; Flávia Castro Ribas de Souza; Silvia Fukuzaki; Maysa Mariana Cruz; Maria Isabel Cardoso Alonso-Vale; Beatriz Mangueira Saraiva-Romanholo; Carla Máximo Prado; Mílton de Arruda Martins; Edna Aparecida Leick; Iolanda de Fátima Lopes Calvo Tibério
Journal:  Front Immunol       Date:  2018-01-05       Impact factor: 7.561

3.  A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages.

Authors:  Carian E Boorsma; T Anienke van der Veen; Kurnia S S Putri; Andreia de Almeida; Christina Draijer; Thais Mauad; Gyorgy Fejer; Corry-Anke Brandsma; Maarten van den Berge; Yohan Bossé; Don Sin; Ke Hao; Anja Reithmeier; Göran Andersson; Peter Olinga; Wim Timens; Angela Casini; Barbro N Melgert
Journal:  Sci Rep       Date:  2017-10-03       Impact factor: 4.379

  3 in total

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