Literature DB >> 18642833

Consecutive cyclization of allylaminoalkene by intramolecular aminolithiation-carbolithiation.

Susumu Tsuchida1, Atsunori Kaneshige, Tokutaro Ogata, Hiromi Baba, Yasutomo Yamamoto, Kiyoshi Tomioka.   

Abstract

Consecutive cyclization of allylaminoalkenes by tandem aminolithiation-carbolithiation proceeded smoothly by using a lithium amide as a lithiating agent as well as protonating agent to give bicyclic amines, octahydroindolizine and hexahydro-1 H-pyrrolizine, in reasonably high yield and diastereoselectivity.

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Year:  2008        PMID： 18642833     DOI： 10.1021/ol801397v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Thieno[2,3-d]pyrimidinedione derivatives as antibacterial agents.

Authors:  Mahender B Dewal; Amit S Wani; Celine Vidaillac; David Oupický; Michael J Rybak; Steven M Firestine
Journal:  Eur J Med Chem       Date:  2012-02-25       Impact factor: 6.514

2.  Synthetic and Computational Study of Tin-Free Reductive Tandem Cyclizations of Neutral Aminyl Radicals.

Authors:  Hansamali S Sirinimal; Sebastien P Hebert; Ganesh Samala; Heng Chen; Gregory J Rosenhauer; H Bernhard Schlegel; Jennifer L Stockdill
Journal:  Org Lett       Date:  2018-09-28       Impact factor: 6.005
  2 in total

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