Literature DB >> 18641869

Sleep apnea and REM sleep behavior disorder in patients with Chiari malformations.

Paulo Sérgio A Henriques-Filho1, Riccardo Pratesi.   

Abstract

BACKGROUND: Chiari malformations (CM) may result in the appearance of REM sleep behavior disorder (RBD) and sleep apnea syndrome (SAS) that can be considered markers of brain stem dysfunction.
PURPOSE: To evaluate the frequency of RBD and SAS in patients with CM type I and II.
METHOD: Were evaluated 103 patients with CM by means of full night polysomnography. Were scoring different sleep stages, frequency of abnormal movements (through video monitoring) and abnormal respiratory events.
RESULTS: Of the 103 patients, 36 showed CM type I and 67 CM type II. Episodes of RBD were observed in 23 patients. Abnormal apnea-hypopnea index (AHI) was observed in 65 patients.
CONCLUSION: The high rate of RBD suggests that this parassomnia and the increased frequency of central sleep apnea episodes, may be considered as a marker of progressive brain stem dysfunction.

Entities:  

Mesh:

Year:  2008        PMID: 18641869     DOI: 10.1590/s0004-282x2008000300012

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


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