Literature DB >> 18641854

Lupus vulgaris in a pediatric patient: a clinicohistopathological diagnosis.

F Sule Afsar1, Ilhan Afsar, Gulden Diniz, Suna Asilsoy, Yelda Sorguc.   

Abstract

Lupus vulgaris is the most common form of cutaneous tuberculosis which usually occurs in patients previously sensitized to Mycobacterium tuberculosis. We present a case of a 10-year-old boy who was diagnosed as lupus vulgaris clinically and histopathologically. He had well demarcated, irregularly bordered, pink, infiltrated plaques on his left cheek showing apple-jelly appearance on diascopy. The histopathological examination showed tuberculoid granulomas with Langhans type giant cells. The Mantoux reactivity was in normal limits, and no acid-fast bacilli was found in the lesion, either by direct stained smears or by culture. The lesions showed marked improvement on anti-tuberculosis treatment. We want to emphasize that histopathological examination has diagnostic value in lupus vulgaris in correlation with clinical appearance, when direct analysis or culture is negative.

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Year:  2008        PMID: 18641854     DOI: 10.1590/s1413-86702008000200011

Source DB:  PubMed          Journal:  Braz J Infect Dis        ISSN: 1413-8670            Impact factor:   1.949


  2 in total

1.  Cutaneous tuberculosis caused by isoniazid-resistant Mycobacterium tuberculosis.

Authors:  Mehrnaz Asadi Gharabaghi
Journal:  BMJ Case Rep       Date:  2012-07-03

2.  Novel Approach for Transdermal Delivery of Rifampicin to Induce Synergistic Antimycobacterial Effects Against Cutaneous and Systemic Tuberculosis Using a Cationic Nanoemulsion Gel.

Authors:  Afzal Hussain; Mohammad A Altamimi; Sultan Alshehri; Syed Sarim Imam; Faiyaz Shakeel; Sandeep Kumar Singh
Journal:  Int J Nanomedicine       Date:  2020-02-14
  2 in total

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