Literature DB >> 18641529

Supraglottoplasty for laryngomalacia with obstructive sleep apnea.

Mark E Zafereo1, Rodney J Taylor, Kevin D Pereira.   

Abstract

OBJECTIVES/HYPOTHESIS: To determine if supraglottoplasty (SGP) is effective in reversing abnormal respiratory parameters in children with laryngomalacia and obstructive sleep apnea (OSA). STUDY
DESIGN: Retrospective case series at a tertiary referral children's hospital.
METHODS: Ten patients with laryngomalacia and OSA as documented by polysomnography underwent SGP between 2005 and 2007. Data collected included age, findings on flexible and rigid endoscopy, type of procedure performed, and postoperative course. The postoperative polysomnographies were reviewed to identify changes in obstructive apnea index, obstructive apnea/hypopnea index, respiratory disturbance index, and low arterial oxygen saturation (O2 nadir) after SGP.
RESULTS: All 10 patients were successfully extubated after SGP. There were no peri- or postoperative complications, and no patient required a subsequent airway procedure. Each patient had a postoperative nocturnal polysomnography performed after SGP at 11 weeks (range 2-29 weeks). Caregivers reported mild improvement (10%), significant improvement (70%), and complete resolution (20%) of stridor and nocturnal snoring at a follow-up visit 4 weeks after discharge. Marked improvements were observed in obstructive apnea index, obstructive apnea/hypopnea index, respiratory disturbance index and O2 nadir, all of which were statistically significant (P < .05).
CONCLUSIONS: Polysomnography should be considered in the initial evaluation of infants with moderate laryngomalacia to rule out OSA. SGP is an effective treatment for infants with laryngomalacia and OSA. The significant benefits of the procedure outweigh thelow morbidity. Improvement after surgery was reliably confirmed by polysomnography in this study.

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Year:  2008        PMID: 18641529     DOI: 10.1097/MLG.0b013e31817e7441

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  9 in total

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Authors:  Eliot S Katz; Ron B Mitchell; Carolyn M D'Ambrosio
Journal:  Am J Respir Crit Care Med       Date:  2011-12-01       Impact factor: 21.405

Review 2.  Executive summary of respiratory indications for polysomnography in children: an evidence-based review.

Authors:  Merrill S Wise; Cynthia D Nichols; Madeleine M Grigg-Damberger; Carole L Marcus; Manisha B Witmans; Valerie G Kirk; Lynn A D'Andrea; Timothy F Hoban
Journal:  Sleep       Date:  2011-03-01       Impact factor: 5.849

Review 3.  Physiological effects of obstructive sleep apnea syndrome in childhood.

Authors:  Hiren Muzumdar; Raanan Arens
Journal:  Respir Physiol Neurobiol       Date:  2013-05-23       Impact factor: 1.931

4.  Polysomnographic Outcomes After Observation for Mild Obstructive Sleep Apnea in Children Younger Than 3 Years.

Authors:  Kathleen M Sarber; Douglas C von Allmen; Raisa Tikhtman; Javier Howard; Narong Simakajornboon; Wenwen Yu; David F Smith; Stacey L Ishman
Journal:  Otolaryngol Head Neck Surg       Date:  2020-09-29       Impact factor: 3.497

Review 5.  Obstructive Sleep Apnea in Neonates.

Authors:  Indira Chandrasekar; Mary Anne Tablizo; Manisha Witmans; Jose Maria Cruz; Marcus Cummins; Wendy Estrellado-Cruz
Journal:  Children (Basel)       Date:  2022-03-15

Review 6.  Sleep disordered breathing at the extremes of age: infancy.

Authors:  Don S Urquhart; Hui-Leng Tan
Journal:  Breathe (Sheff)       Date:  2016-03

7.  Changes in Breathing Patterns after Surgery in Severe Laryngomalacia.

Authors:  Fabrizio Cialente; Duino Meucci; Maria Luisa Tropiano; Antonio Salvati; Miriam Torsello; Ferdinando Savignoni; Francesca Landolfo; Andrea Dotta; Marilena Trozzi
Journal:  Children (Basel)       Date:  2021-12-03

8.  Surgical treatment of severe laryngomalacia: a retrospective study of 11 case.

Authors:  José Antonio Pinto; Henrique Wambier; Elcio Izumi Mizoguchi; Leonardo Marques Gomes; Rodrigo Kohler; Renata Coutinho Ribeiro
Journal:  Braz J Otorhinolaryngol       Date:  2013 Sep-Oct

9.  Laryngomalacia surgery: a series from a tertiary pediatric hospital.

Authors:  José Faibes Lubianca Neto; José Faibes Lubianca Netto; Renata Loss Drummond; Luciana Pimentel Oppermann; Fernando Stahl Hermes; Rita Carolina Pozzer Krumenauer
Journal:  Braz J Otorhinolaryngol       Date:  2012-12
  9 in total

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