Literature DB >> 18641525

Skull base osteomyelitis: the effect of comorbid disease on hospitalization.

Vanessa S Rothholtz1, Alice D Lee, Bahman Shamloo, Mohsen Bazargan, Deya Pan, Hamid R Djalilian.   

Abstract

OBJECTIVES/HYPOTHESIS: Skull base osteomyelitis is a rare disease that has a high morbidity and mortality rate if diagnosis and treatment are delayed. Our objective was to perform a more detailed analysis of skull base osteomyelitis in the inpatient population. We also provide a more comprehensive evaluation of comorbid disease and severity of illness in this population and describe their effects on the duration and cost of hospital stay. STUDY
DESIGN: Review of the California Hospital Discharge Database between the years 1990 and 2000.
METHODS: Information evaluated included age, race, insurance, charges and length of hospital stay, comorbid disease, severity of illness, and disposition. Data were analyzed using analysis of variance and linear regression analysis.
RESULTS: The overall incidence of skull base osteomyelitis ranged from 57 to 95 cases annually (median 75.5). Whites (69.3%) were more likely to present with the disease than Native Americans (13.2%), African Americans (6.5%), or Asians (2.9%). The majority of patients diagnosed with skull base osteomyelitis had Medicare or public assistance (62%) compared with those with Preferred Provider Organization or Health Maintenance Organization insurance (27%). Increased length of hospital stay and increased charges incurred during hospitalization were significantly associated (P < .05) with aplastic anemia, renal disease, arteriosclerosis, facial nerve dysfunction, and diabetes. Severity of illness and the presence of one or more comorbid conditions also significantly affected the duration and charges incurred during hospital stay (P < .05).
CONCLUSIONS: The presence of concurrent illness with skull base osteomyelitis significantly affects the duration of hospital stay and the charges incurred during hospitalization.

Entities:  

Mesh:

Year:  2008        PMID: 18641525     DOI: 10.1097/MLG.0b013e31817fae0d

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  14 in total

1.  Central skull base osteomyelitis: new insights and implications for diagnosis and treatment.

Authors:  Gerd J Ridder; Christine Breunig; Jan Kaminsky; Jens Pfeiffer
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-11-09       Impact factor: 2.503

2.  Skull base osteomyelitis and potential cerebrovascular complications in children.

Authors:  Mariasavina Severino; Sidath Liyanage; Vas Novelli; Beth Cheesborough; Dawn Saunders; Roxana Gunny; Andrea Rossi
Journal:  Pediatr Radiol       Date:  2012-03-17

3.  Predictive factors in treatment response of malignant external otitis.

Authors:  Alireza Zonnour; Abolfazl Jamshidi; Sasan Dabiri; Mehrdad Hasibi; Ardavan Tajdini; Narges Karrabi; Nasrin Yazdani
Journal:  Eur Arch Otorhinolaryngol       Date:  2022-06-25       Impact factor: 2.503

4.  Skull base osteomyelitis in the emergency department: a case report.

Authors:  Mustafa Burak Sayhan; Cemil Kavalci; Ozgur Sogüt; Eylem Sezenler
Journal:  Emerg Med Int       Date:  2011-05-29       Impact factor: 1.112

5.  Severe skull base osteomyelitis caused by Pseudomonas aeruginosa with successful outcome after prolonged outpatient therapy with continuous infusion of ceftazidime and oral ciprofloxacin: a case report.

Authors:  Cristina Conde-Díaz; Jara Llenas-García; Mónica Parra Grande; Gertrudis Terol Esclapez; Mar Masiá; Félix Gutiérrez
Journal:  J Med Case Rep       Date:  2017-02-21

6.  Skull base osteomyelitis: factors implicating clinical outcome.

Authors:  Jacek Sokołowski; Magdalena Lachowska; Emilia Karchier; Robert Bartoszewicz; Kazimierz Niemczyk
Journal:  Acta Neurol Belg       Date:  2019-03-06       Impact factor: 2.396

Review 7.  Skull Base Osteomyelitis: A Comprehensive Imaging Review.

Authors:  P R Chapman; G Choudhary; A Singhal
Journal:  AJNR Am J Neuroradiol       Date:  2021-01-21       Impact factor: 3.825

8.  Temporomandibular joint disorder from skull-base osteomyelitis: a case report.

Authors:  Suck-Chul Lee; Jae-Hyung Kim; Chul-Hoon Kim; Bok-Joo Kim
Journal:  Maxillofac Plast Reconstr Surg       Date:  2015-10-31

Review 9.  A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations.

Authors:  Muhammad Adnan Khan; Syed Abdul Qader Quadri; Abdulmuqueeth Syed Kazmi; Vishal Kwatra; Anirudh Ramachandran; Aaron Gustin; Mudassir Farooqui; Sajid Sattar Suriya; Atif Zafar
Journal:  Asian J Neurosurg       Date:  2018 Oct-Dec

10.  The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans.

Authors:  J Mejzlik; M Cerny; L Zeinerova; J Dedkova; J Kopriva; K Zadrobilek; J Adamkov; V Chrobok; V Pellantova
Journal:  BMC Med Imaging       Date:  2019-08-01       Impact factor: 1.930

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