Literature DB >> 18640470

A retrospective analysis of the prevalence and treatment of hypertension and dyslipidemia in Southwestern Ontario, Canada.

Robert J Petrella1, Elizabeth Merikle.   

Abstract

BACKGROUND: Previous evaluations of the Southwestern Ontario (SSWO) cohort have reported that hypertension (HTN) and dyslipidemia (DYS) are undertreated illnesses; however, concomitant treatment is unknown.
OBJECTIVES: The objectives of this study were to assess the prevalence and associated treatment of HTN and DYS in primary health care in SWO and to identify care gaps across subpopulations.
METHODS: In this retrospective cohort analysis, chart-abstracted medical records of patients aged>or=118 years with a clinical diagnosis of HTN, DYS, or both and the clinical practice records of primary health care facilities in London, Ontario, Canada, and the surrounding area were conducted between April and December 2000; longitudinal updates were performed quarterly until December 2004. Chart-abstracted information included demographics, lifestyle (eg, diet, exercise), cardiovascular disease indicators, complete morbidity profile, and drug treatments and effects.
RESULTS: The medical records of 46,322 patients who received medical care and the clinical practice records of 37 primary health care facilities (where the patients received treatment) in London, Ontario, Canada, and the surrounding area were included in this study. Our analyses found that the prevalence of HTN (17.66%) was greater than that of DYS (12.33%); with comorbid HTN and DYS found in 8.0% of the population. Most hypertensive patients were not dyslipidemic (54.88%), but more than half of dyslipidemic patients had comorbid HTN (64.99%). Significant differences in prevalence among the sex, age, and comorbid subgroups were found. HTN was higher among females than males (P<0.001) but lower among female smokers than male smokers (P<0.001). Patients aged >55 years were much more likely to be hypertensive, dyslipidemic, or both compared with those aged <55 years (P<0.009), except among those patients with a family history of coronary heart disease (CHD). Additionally, a steady increase in HTN and DYS prevalence with age by decade until 75 years of age, after which the rates dropped off, was observed. Most patients were untreated for HTN (66.00%) or DYS (80.00%) unless both conditions were present (35.00% untreated for HTN; 39.00% untreated for DYS). Among patients with comorbid HTN and DYS, the order of diagnosis had a significant effect on treatment level. The presence of other comorbidities (eg, family history of CHD) resulted in higher treatment and control rates. Control levels were generally poor, with 7.0% among patients with DYS, 15.00% among patients with HTN, and 17.00% among patients with both conditions.
CONCLUSIONS: Treatment patterns of HTN and DYS in practice settings are not in alignment with current guidelines in this cohort. Pharmacologic treatment of HTN and DYS is underprescribed. Patients most likely to receive treatment have comorbidities, but even in those high-risk groups, treatment levels are low and recommended control levels even lower.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18640470     DOI: 10.1016/j.clinthera.2008.06.004

Source DB:  PubMed          Journal:  Clin Ther        ISSN: 0149-2918            Impact factor:   3.393


  18 in total

1.  Diabetes and Technology for Increased Activity (DaTA) study: results of a remote monitoring intervention for prevention of metabolic syndrome.

Authors:  Melanie Stuckey; Elizabeth Russell-Minda; Emily Read; Claudio Munoz; Kevin Shoemaker; Peter Kleinstiver; Robert Petrella
Journal:  J Diabetes Sci Technol       Date:  2011-07-01

2.  Remote monitoring technologies for the prevention of metabolic syndrome: the Diabetes and Technology for Increased Activity (DaTA) study.

Authors:  Melanie Stuckey; Robyn Fulkerson; Emily Read; Elizabeth Russell-Minda; Claudio Munoz; Peter Kleinstiver; Robert Petrella
Journal:  J Diabetes Sci Technol       Date:  2011-07-01

Review 3.  Risk factors preceding type 2 diabetes and cardiomyopathy.

Authors:  Shamjeet Singh; Sanjiv Dhingra; Dan D Ramdath; Sudesh Vasdev; Vicki Gill; Pawan K Singal
Journal:  J Cardiovasc Transl Res       Date:  2010-07-01       Impact factor: 4.132

4.  Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades.

Authors:  Finlay A McAlister; Kathryn Wilkins; Michel Joffres; Frans H H Leenen; George Fodor; Marianne Gee; Mark S Tremblay; Robin Walker; Helen Johansen; Norm Campbell
Journal:  CMAJ       Date:  2011-05-16       Impact factor: 8.262

5.  A randomized trial of a community-based approach to dyslipidemia management: Pharmacist prescribing to achieve cholesterol targets (RxACT Study).

Authors:  Ross T Tsuyuki; Meagen Rosenthal; Glen J Pearson
Journal:  Can Pharm J (Ott)       Date:  2016-08-02

6.  Demographic Characteristics and Patterns of Medication in Atrial Fibrillation Patients in South West Ontario: Insights from a Large Primary Care Database.

Authors:  Robert J Petrella; Luc Sauriol
Journal:  J Atr Fibrillation       Date:  2012-04-14

Review 7.  Practical use of the Framingham risk score in primary prevention: Canadian perspective.

Authors:  N John Bosomworth
Journal:  Can Fam Physician       Date:  2011-04       Impact factor: 3.275

8.  Practical Applications for Single Pill Combinations in the Cardiovascular Continuum.

Authors:  Ferdinando Iellamo; Karl Werdan; Krzysztof Narkiewicz; Giuseppe Rosano; Maurizio Volterrani
Journal:  Card Fail Rev       Date:  2017-04

9.  The impact of cardiovascular risk-factor profiles on blood pressure control rates in adults from Canada and the United States.

Authors:  Finlay A McAlister; Cynthia Robitaille; Cathleen Gillespie; Keming Yuan; Deepa P Rao; Steven Grover; Sulan Dai; Helen Johansen; Michel Joffres; Fleetwood Loustalot; Norm Campbell
Journal:  Can J Cardiol       Date:  2013-03-01       Impact factor: 5.223

10.  Diagnosis and Control of Hypertension as Indicators of the Level of Awareness Among Relatives of Medical Students in Saudi Arabia.

Authors:  Ahmad A Mirza; Soha A Elmorsy
Journal:  High Blood Press Cardiovasc Prev       Date:  2016-04-29
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.