Literature DB >> 186401

Mode of interaction of different polyanions with the first (C1,C1) the second (C2) and the fourth (C4) component of complement. IV. Activation of C1 in serum by polyanions.

M Loos, D Bitter-Suermann.   

Abstract

Treatment of serum with dextransulphate polyvinylsulphate or polyanetholsulphonate resulted in a dose-dependent activation of C1 and C3; this was found for normal serum as well as for C4-deficient guinea-pig serum. Activation of C1 and C3 occurred at the same concentration of polyanions. The consumption of C3 in C4 deficient serum and the requirement of factor D of the alternative pathway indicate that C3 is activated via the alternative pathway.

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Year:  1976        PMID: 186401      PMCID: PMC1445175     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  9 in total

1.  Mode of interaction of different polyanions with the first (C1, C1), the second (C2) and the fourth (C4) component of complement--II. Effect of polyanions on the binding of C2 to EAC4b.

Authors:  M Loos; J E Volanakis; R M Stroud
Journal:  Immunochemistry       Date:  1976-03

2.  Mode of interaction of different polyanions with the first (C1, C1), the second (C2) and the fourth (C4) component of complement--I. Effect on fluid phase C1 and on C1 bound to EA or to EAC4.

Authors:  E Raepple; H U Hill; M Loos
Journal:  Immunochemistry       Date:  1976-03

3.  Mode of interaction of different polyanions with the first (C1, C1), the second (C2) and the fourth (C4) component of complement--III. Inhibition of C4 and C2 binding site(s) on C1s by polyanions.

Authors:  M Loos; J E Volanakis; R M Stroud
Journal:  Immunochemistry       Date:  1976-09

4.  Factor D in the alternate pathway of complement activation: purification, physicochemical characterization and functional role.

Authors:  M P Dierich; U Hadding; W König; M Limbert; H U Schorlemmer; D Bitter-Suermann
Journal:  Immunochemistry       Date:  1974-09

5.  Ability of the T cell-replacing polyanion dextran sulfate to trigger the alternate pathway of complement activation.

Authors:  U Hadding; M Dierich; W König; M Limbert; H U Schorlemmer; D Bitter-Suermann
Journal:  Eur J Immunol       Date:  1973-08       Impact factor: 5.532

6.  Bypass-activation of the complement system starting with C3. I. Generation and function of an enzyme from a factor of guinea-pig serum and cobra venom.

Authors:  D Bitter-Suermann; M Dierich; W König; U Hadding
Journal:  Immunology       Date:  1972-09       Impact factor: 7.397

7.  Complement activation by interaction of polyanions and polycations. I. Heparin-protamine induced consumption of complement.

Authors:  R Rent; N Ertel; R Eisenstein; H Gewurz
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

8.  Complement activation by interaction of polyanions and polycations.

Authors:  B A Fiedel; R Rent; R Myhrman; H Gewurz
Journal:  Immunology       Date:  1976-02       Impact factor: 7.397

9.  Dextran sulphate: a synthetic activator of C3 via the alternative pathway. I. Influence of molecular size and degree of sulphation on the activation potency.

Authors:  R Burger; U Hadding; H U Schorlemmer; V Brade; D Bitter-Suermann
Journal:  Immunology       Date:  1975-09       Impact factor: 7.397

  9 in total
  6 in total

1.  Insoluble polyanions as activators of both pathways of complement.

Authors:  R Burger; D Bitter-Suermann; M Loos; U Hadding
Journal:  Immunology       Date:  1977-12       Impact factor: 7.397

2.  Induction of proteolytic activity in serum by treatment with anionic detergents and organic solvents.

Authors:  D Berger; T L Vischer; A Micheli
Journal:  Experientia       Date:  1983-10-15

3.  Sodium polyanethole sulfonate as an inhibitor of activation of complement function in blood culture systems.

Authors:  Yaseelan Palarasah; Mikkel-Ole Skjoedt; Lars Vitved; Thomas Emil Andersen; Karsten Skjoedt; Claus Koch
Journal:  J Clin Microbiol       Date:  2009-12-30       Impact factor: 5.948

4.  In vitro complement binding on cytoplasmic structures in normal human skin: immunoelectronmicroscopic studies.

Authors:  G Schuler; H Hintner; K Wolff; P Fritsch; G Stingl
Journal:  J Cell Biol       Date:  1982-11       Impact factor: 10.539

5.  MASP-2 Is a Heparin-Binding Protease; Identification of Blocking Oligosaccharides.

Authors:  Ditmer T Talsma; Felix Poppelaars; Wendy Dam; Anita H Meter-Arkema; Romain R Vivès; Peter Gál; Geert-Jan Boons; Pradeep Chopra; Annamaria Naggi; Marc A Seelen; Stephan P Berger; Mohamed R Daha; Coen A Stegeman; Jacob van den Born
Journal:  Front Immunol       Date:  2020-04-28       Impact factor: 7.561

6.  Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway.

Authors:  Sanjay Khandelwal; Joann Ravi; Lubica Rauova; Alexandra Johnson; Grace M Lee; Jennifer B Gilner; Sreenivasulu Gunti; Abner L Notkins; Maragatha Kuchibhatla; Michael Frank; Mortimer Poncz; Douglas B Cines; Gowthami M Arepally
Journal:  Blood       Date:  2018-10-11       Impact factor: 25.476

  6 in total

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