Literature DB >> 1863989

Estimates of heritability of plasma homocyst(e)ine levels in aging adult male twins.

T Reed1, M R Malinow, J C Christian, B Upson.   

Abstract

Plasma homocyst(e)ine level was determined for 96 identical (MZ) and 92 fraternal (DZ) adult male twins aged 59-69. There was no difference in mean between MZ (10.31 nmol/ml) and DZ (10.36 nmol/ml) twins. The intraclass correlation coefficient of the log-transformed homocyst(e)ine level in 43 complete MZ and 39 complete DZ pairs was 0.55 and 0.19, respectively. The MZ correlation was significantly (p less than 0.05) greater than the DZ correlation, suggesting that the level of plasma homocyst(e)ine is genetically influenced.

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Year:  1991        PMID: 1863989     DOI: 10.1111/j.1399-0004.1991.tb03053.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN: 0009-9163            Impact factor:   4.438


  3 in total

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Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2020-06-08       Impact factor: 5.270

  3 in total

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